Synopsis of recent research by authors named "Yayan Hou"
- Yayan Hou's recent research focuses on understanding the mechanisms behind cancer development and chronic kidney disease, specifically examining the role of proteins and receptors in these conditions.
- In a study published in 2024, Hou demonstrated that the ablation of the WDR61 gene significantly reduces breast cancer progression by triggering R-loop accumulation, which leads to smaller tumor sizes and improved survival rates in animal models.
- In a 2020 study, Hou explored the inhibition of α1-adrenoceptors, revealing that this approach effectively reduces TGF-β1-induced epithelial-to-mesenchymal transition and renal fibrosis in mice, highlighting a potential therapeutic target in chronic kidney disease.