Aurantiamide mitigates acute kidney injury by suppressing renal necroptosis and inflammation via GRPR-dependent mechanism.

Acute kidney injury (AKI) manifests as a clinical syndrome characterised by the rapid accumulation of metabolic wastes, such as blood creatinine and urea nitrogen, leading to a sudden decline in renal function. Currently, there is a lack of specific therapeutic drugs for AKI. Previously, we identified gastrin-releasing peptide receptor (GRPR) as a pathogenic factor in AKI.

Enhanced charge transfer and photocatalytic carbon dioxide reduction of copper sulphide@cerium dioxide p-n heterojunction hollow cubes.

Hollow structure hybrids have gained considerable attention for their ability to reduce CO owing to their rich active sites, high gas adsorption ability, and excellent light utilization capacity. Herein, a template-engaged strategy was provided to fabricate copper sulphide@cerium dioxide (CuS@CeO) p-n heterojunction hollow cube photocatalysts using CuO cubes as a sacrificial template. The sequential steps of loading of CeO nanolayer, sulfidation, and etching reaction facilitate the formation of CuS@CeO p-n heterojunction hollow cubes.