Publications by authors named "Yawen Bian"
Cervical high-grade squamous intraepithelial lesions (HSIL) are one of the common types of cervical cancer precancerous changes, and HPV16/18 positivity is a risk factor for HSIL recurrence. By detecting the expression of relevant markers in the lesion tissue of recurrent patients, it is helpful for the diagnosis of HPV16/18 positivity and can provide a basis for disease recurrence risk assessment. Therefore, this study analyzed the relationship between p16, C-myc, PIK3CA proteins and HPV16/18 positivity in recurrent cervical HSIL patients.
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- - GNL3 is an RNA binding protein that plays a role in stem cell proliferation and is linked to apoptosis; its exact function in psoriasis vulgaris, a chronic inflammatory skin condition, is not well understood.
- - Research utilized RNA-seq to analyze gene expression and splicing events in cells with altered GNL3 levels, revealing significant changes in the expression of IL23A and TNFAIP3 related to GNL3 activity.
- - The findings suggest that GNL3 is crucial in the development of psoriasis vulgaris by influencing the IL23/IL17 signaling pathway, indicating potential targets for future treatments.
Osteoarthritis (OA) is a degenerative disease, which has a high incidence in middle-aged and elderly people and tends to occur in weight-bearing or active joints. Current treatment can only relieve symptoms and delay the progression of OA in result of its indistinct pathogenesis. In recent years, more and more studies have focused on the pathogenesis of OA.
View Article and Find Full Text PDFBackground: In recent years, methylene blue mediated-photodynamic therapy (MB-PDT) has proved to be an effective inhibitor to a variety of microorganisms, including Trichophyton rubrum, the most common dermatophyte worldwide. However, previous studies mainly focused on the spore form of T rubrum, but rarely on its hyphal form, although the latter is the main pathogenic form of T rubrum in vivo.
Objective: To investigate the inhibitory effect of MB-PDT on T rubrum in different growth phases in vitro.