Publications by authors named "Yau Fong Chan"
Article Synopsis
- The SiaA protein in Streptococcus pyogenes is involved in heme uptake and was studied through mutations to understand how these changes affect heme binding.
- pH titrations revealed that mutations led to similar pKa values compared to the wild-type, but resonant Raman spectra indicated a different heme environment in the mutants.
- The study suggests that the unfolding of SiaA is influenced by the interaction strength of its amino acid residues with heme, proposing a mechanism where minor structural changes allow for heme release while maintaining overall protein stability for ongoing heme trafficking.
Quenching and sensitizing fullerene photoreactions by natural organic matter.
Environ Sci Technol
June 2013
Effects of natural organic matter (NOM) on the photoreaction kinetics of fullerenes (i.e., C60 and fullerenol) were investigated using simulated sunlight and monochromatic radiation (365 nm).
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