Publications by authors named "Yatsiri G Meneses-Preza"
Tuberculosis (TB) is a global health problem with diverse clinical manifestations. Different cells of the immune response participate in containing the infection, mainly through the development of granulomas. Mast cells (MCs) are hematopoietic cells that participate in the immune response to different pathogens, and in vitro evidence indicates that they can be activated by Mycobacterium tuberculosis (Mtb).
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- COVID-19, caused by the SARS-CoV-2 virus, triggers an uncontrolled immune response that leads to harmful inflammation and lung damage.
- Mast cells (MCs), known for their role in inflammation, are linked to severe COVID-19 cases, particularly through their mediator carboxypeptidase A3 (CPA3).
- The study found that in severe COVID-19 cases, increased CPA3-expressing MCs correlate with the development of pulmonary fibrosis (PF), indicating that excessive inflammation contributes to ongoing tissue damage and impaired healing.
Mast cells (MC) play a central role in the early containment of bacterial infections, such as that caused by Listeria monocytogenes (L.m). The mechanisms of MC activation induced by L.
View Article and Find Full Text PDF(L.m) is efficiently controlled by several cells of the innate immunity, including the Mast Cell (MC). MC is activated by L.
View Article and Find Full Text PDFThe immune response plays a critical role in the pathophysiology of SARS-CoV-2 infection ranging from protection to tissue damage and all occur in the development of acute respiratory distress syndrome (ARDS). ARDS patients display elevated levels of inflammatory cytokines and innate immune cells, and T and B cell lymphocytes have been implicated in this dysregulated immune response. Mast cells are abundant resident cells of the respiratory tract and are able to release different inflammatory mediators rapidly following stimulation.
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