Deciphering ferroptosis in critical care: mechanisms, consequences, and therapeutic opportunities.

Ischemia-reperfusion injuries (IRI) across various organs and tissues, along with sepsis, significantly contribute to the progression of critical illnesses. These conditions disrupt the balance of inflammatory mediators and signaling pathways, resulting in impaired physiological functions in human tissues and organs. Ferroptosis, a distinct form of programmed cell death, plays a pivotal role in regulating tissue damage and modulating inflammatory responses, thereby influencing the onset and progression of severe illnesses.

Adiposity indicators exhibit depot- and sex-specific associations with multimorbidity onset: A cohort study of the UK Biobank.

Aim: This study investigated the depot- and sex-specific associations of adiposity indicators with incident multimorbidity and comorbidity pairs.

Materials And Methods: We selected 382 678 adults without multimorbidity (≥2 chronic diseases) at baseline from the UK Biobank. General obesity, abdominal obesity and body fat percentage indices were measured.

Psychological Stress and Gut Microbiota Composition: A Systematic Review of Human Studies.

Introduction: The associations between psychological stress and gut microbiota composition are not fully understood. This study investigated associations between psychological stress and gut microbiota composition and examined the potential modifying effects of age, sex, and ethnicity on such associations.

Methods: A systematic literature search was conducted using PubMed, Web of Science, PsycINFO, and Embase databases for studies published until November 2021 which examined associations between psychological stress and gut microbiota composition.

Synthesis of Fe/FeO@porous carbon through a facile heat treatment of iron-containing candle soots for peroxymonosulfate activation and efficient degradation of sulfamethoxazole.

Developing highly efficient, reusable, non-toxic and low-cost catalysts is of great importance for persulfate-based advanced oxidation processes (AOPs). In this work, ferrocene was mixed into paraffin to prepare a candle, and the iron-containing candle soots were collected and heated at 500 °C~900 °C under N atmosphere for 1 h to prepare magnetically recyclable Fe/FeO@porous carbon (Fe/FeO@PC) catalysts. The Fe/FeO@PC-700 obtained after pyrolysis at 700 °C exhibited the best catalytic activity for sulfamethoxazole (SMX) degradation.

Thermally treated candle soot as a novel catalyst for hydrogen peroxide in-situ production enhancement in the bio-electro-Fenton system.

Thermally treated candle soot (TCS) was used as a two-electron (2e¯) oxygen reduction reaction (ORR) catalyst to in situ produce HO in a bio-electro-Fenton (BEF) system. Compared with the pristine candle soot (CS), TCS showed larger Brunauer-Emmett-Teller (BET) surface area (102.54 m g vs.

Levels of central oxytocin and glucocorticoid receptor and serum adrenocorticotropic hormone and corticosterone in mandarin voles with different levels of sociability.

Sociability is the prerequisite to social living. Oxytocin and the hypothalamo-pituitary-adrenocortical axis mediate various social behaviors across different social contexts in different rodents. We hypothesized that they also mediate levels of non-reproductive social behavior.

Sociality and oxytocin and vasopressin in the brain of male and female dominant and subordinate mandarin voles.

The dominant-subordinate hierarchy in animals often needs to be established via agonistic encounters and consequently affects reproduction and survival. Differences in brain neuropeptides and sociality among dominant and subordinate males and females remain poorly understood. Here we explore neuropeptide levels and sociality during agonistic encounter tests in mandarin voles.