Publications by authors named "Yat Yin Chau"
J Biol Chem
November 2024
Article Synopsis
- * Mutations in Rab23, such as M12K, C85R, and Y79del, occur within its GTPase domain and affect its function, but the exact activation mechanisms and how these mutations lead to disease are not fully understood.
- * High-resolution crystal structures of human Rab23 and the Y79del mutant have been determined, showing that the deletion leads to structural changes that disrupt its interactions with partners, contributing to its loss of function in Carpenter Syndrome.
