Medial-pivot design does not provide superior clinical results compared to posterior-stabilized total knee arthroplasty despite kinematic differences during step-up and lunge activities: A prospective randomized controlled trial under medial tight soft tissue balance.

Purpose: This study aimed to compare in vivo kinematics during weight-bearing daily activities and determine the relationship with clinical outcomes in patients undergoing total knee arthroplasty (TKA) with a medial-pivot (MP, Evolution™) versus a posterior-stabilized (PS, Persona®) design under constant conditions of intraoperative soft tissue balance.

Methods: Forty patients undergoing MP or PS-TKA under similar conditions of soft tissue balance were enrolled in this prospective randomized controlled trial. Outcome measures included clinical knee society scores (KSS) and knee injury and osteoarthritis outcome scores (KOOS).

Articular cartilage lesions increase early cartilage degeneration in knees treated by anterior cruciate ligament reconstruction: T1ρ mapping evaluation and 1-year follow-up.

Background: Articular cartilage degeneration can develop after anterior cruciate ligament reconstruction (ACLR). Although radiological studies have identified risk factors for the progression of degenerative cartilage changes in the long term, risk factors in the early postoperative period remain to be documented.

Hypothesis: Cartilage lesions that are present at surgery progress to cartilage degeneration in the early phase after ACLR.

An analysis of surface profile for cylindrical osteochondral grafts of the knee quantitative evaluation using a three-dimensional laser scanner.

Purpose: To investigate the congruency of the articular cartilage surface of the knee between the recipient and donor site during autogenous osteochondral grafting using a three-dimensional (3D) laser scanning.

Methods: Six cadaveric knees were included in this study. The 3D profiles of the articular surface were obtained by a 3D laser scanner (FastSCAN(®), Polhemus).

T1ρ and T2 mapping of the proximal tibiofibular joint in relation to aging and cartilage degeneration.

Objective: To study the effects of aging and cartilage degeneration of the proximal tibiofibular- and femorotibial joint (PTFJ, FTJ) on the cartilage of the PTFJ using T(1)ρ and T(2) mapping.

Materials And Methods: We performed sagittal T(1)ρ and T(2) mapping of the PTFJ and FTJ on 55 subjects with knee disorders. We placed 3 regions of interest (ROIs) on images of the cartilage in the PTFJ, medial femoral condyle (MFC), and medial tibia plateau (MTP).

T1ρ and T2 mapping reveal the in vivo extracellular matrix of articular cartilage.

Purpose: To determine the relationship between changes in the extracellular matrix (ECM) and T(1ρ) and T(2) values in vivo. The ECM is composed of proteoglycan (PG), collagen, and water. It has been unclear which of the ECM constituents affects T(1ρ) and T(2) mapping in living human cartilage.

Diabetes with hyperlipidemia: a risk factor for developing joint contractures secondary to immobility in rat knee joints?

Several studies have reported that diabetes may cause limited joint motion and often combines with hyperlipidemia (HL). This study clarifies that joint contracture can be produced by diabetes, HL, or both. The experimental animal model, a rat with diabetes and HL, was developed by streptozosin injection and addition of 1% cholesterol to the food.

The effect of perfusion with UW solution on the skeletal muscle and vascular endothelial exocrine function in rat hindlimbs.

Background: The effect of University of Wisconsin (UW) solution perfusion for extremity preservation is still unknown although it is widely used. The purpose of this study is to examine the effect of UW solution perfusion on skeletal muscle preservation in a rat model.

Materials And Methods: Rat hindlimbs were amputated and either preserved with UW solution perfusion (UW perfusion group) or given no perfusion (no-perfusion group) for 5 h at 25 degrees C.

Effect of nitric oxide on the contractile function of rat reperfused skeletal muscle.

Background: The involvement of nitric oxide (NO) in ischemia-reperfusion injury remains controversial and has been reported to be both beneficial and deleterious. The purpose of this study was to examine the contribution of NO and superoxide to skeletal muscle function using an ischemic revascularized hind limb model in rats.

Patients And Materials: Warm ischemia produced by vascular pedicle clamping was sustained for 3 h.