Association of in human saliva with periodontal status and composition of the salivary microbiome including periodontopathogens.

Unlabelled: promotes dental biofilm formation, increases the prevalence of periodontal disease, and is associated with systemic diseases such as colorectal cancer. However, differences in the composition of salivary microbiome among groups based on the abundance of are unclear. Therefore, we analyzed the difference in salivary microbiome among groups based on the abundance of in saliva samples collected from 611 subjects in Japan.

[Antibacterial activity of new-quinolone and macrolide antibiotics against oral bacteria].

Minimum Inhibitory Concentration (MIC) of 4 new-quinolone antibacterial reagents and 4 macrolide antibiotics against periodontopathic bacteria 21 species 24 strains of standard strains including oral related bacteria and clinical isolated (1993-1999) 20 strains of Porphyromonas gingivalis, 7 strains of Actinobacillus actinomycetemcomitans were determined. Minocycline HCl was used as the comparative reagent. Macrolide showed moderate antibacterial activity against standard strains of oral related bacteria except Fusobacterium nucleatum.