[Exposure to 1 % Sevoflurane for 6 Hours Enhances Proliferation of Human Colon Cancer Cells].

Background: Sevoflurane is one of the commonly used volatile anesthetics in cancer patients. The protective effect of sevoflurane preconditioning has raised concerns about whether sevoflurane could act advantageously for survival even of cancer cells. Therefore, we investigated the effects of sevoflurane on proliferation in colon cancer cell lines.

Evaluation of predictive factors associated with increased intraocular pressure during prone position spine surgery.

Background: Intraocular pressure(IOP) has been shown to increase during prone position spine surgery. The present study was conducted to evaluate IOP changes and predictive factors associated with increased IOP during prone position spine surgery.

Methods: After institutional approval and written informed consent, 56 patients undergoing prone position spine surgery were studied.

Effects of morphine and fentanyl on 5-fluorouracil sensitivity in human colon cancer HCT116 cells.

Opioids are widely used for perioperative pain management in cancer surgery patients. It has been reported that opioids may alter cancer recurrence or progression; however, there are no published reports regarding the effects of opioids on chemotherapy after cancer surgery. Here we investigated the effects of opioids (morphine or fentanyl) on cell proliferation and 5-fluorouracil sensitivity in the human colon cancer cell line, HCT116.

Changes in intraocular pressure during prone spine surgery under propofol and sevoflurane anesthesia.

Background: Intraocular pressure (IOP) has been shown to increase during prone spine surgery. Although propofol and sevoflurane have been widely used during such surgery, there have been no data to compare the IOP changes under propofol and sevoflurane anesthesia. The present study was therefore conducted to investigate IOP changes under propofol and sevoflurane anesthesia during prone spine surgery.

Retrospective analysis of predictors of cerebral vasospasm after ruptured cerebral aneurysm surgery: influence of the location of subarachnoid blood.

Purpose: The amount of blood on computed tomography (CT) has been shown to be a predictor of cerebral vasospasm after subarachnoid hemorrhage (SAH). However, the influence of the location of the blood on the incidence of vasospasm remains unclear. We retrospectively assessed the association of the blood volumes in the individual components (cisterns and fissures) of CT scans with angiographic vasospasm after SAH.

[Case of fulminant idiopathic interstitial pneumonia treated by sodium siverlestat (Elaspol) and steroid pulse therapy following extracorporeal lung assist (ECLA)].

A patient with fulminant idiopathic interstitial pneumonia was treated by sodium siverlestat and steroid pulse therapy following extracorporeal lung assist (ECLA). On arriving at the emergency room, Pa(O2) was 44.5 mmHg under oxygen with 10 l reserver mask, and emergency intubation was performed.

[Four cases of diplopia following spinal anesthesia].

Many complications after spinal anesthesia have been reported, but diplopia is rare. We had four cases of diplopia in 794 cases of spinal anesthesia in three years at Nara Medical University Hospital. These 4 cases were not characterized by any major factors including gender, age, or anesthetic choice.

[Effects of low dose colforsin daropate hydrochloride in patients undergoing off-pump coronary artery bypass grafting].

Background: We evaluated retrospectively the effectiveness of low dose colforsin daropate hydrochloride (CDH) in 12 patients undergoing off-pump coronary artery bypass grafting (CABG).

Methods: Low dose CDH was administered intravenously at a rate of 0.05-0.