Image Quality Evaluation in Professional HDR/WCG Production Questions the Need for HDR Metrics.

In the quality evaluation of high dynamic range and wide color gamut (HDR/WCG) images, a number of works have concluded that native HDR metrics, such as HDR visual difference predictor (HDR-VDP), HDR video quality metric (HDR-VQM), or convolutional neural network (CNN)-based visibility metrics for HDR content, provide the best results. These metrics consider only the luminance component, but several color difference metrics have been specifically developed for, and validated with, HDR/WCG images. In this paper, we perform subjective evaluation experiments in a professional HDR/WCG production setting, under a real use case scenario.

Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation.

Activation of the extracellular signal-regulated kinase (ERK) pathway is a key factor in the regulation of cell proliferation by growth factors. Hepatocyte growth factor (HGF)-induced cell cycle arrest in the human hepatocellular carcinoma cell line HepG2 requires strong activation of the ERK pathway. In this study, we investigated the molecular mechanism of the activation.