Publications by authors named "Yasuko Ikeda-Sakai"

Article Synopsis
  • A study analyzed the safety of triptans, medications for migraines, in 128 pregnant women in Japan from 2001 to 2017.
  • The findings showed that miscarriage, low birth weight, preterm birth, and malformations occurred at rates similar to national statistics, indicating no significant added risks from triptan use during pregnancy.
  • This research may help alleviate concerns for pregnant women with migraines who need to use triptans.
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Objectives: Since patients with stroke frequently develop bladder dysfunction, a careful approach is required to reduce unnecessary indwelling urinary catheter (IUC) for preventing catheter-associated urinary tract infection (CAUTI). This study aimed to assess the effectiveness and safety of a program to promote appropriate IUC use in stroke care.

Methods: We conducted a prospective interrupted time series study in three tertiary care hospitals in Japan.

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Article Synopsis
  • An amendment to the original paper has been published.
  • This updated version can be found via a link provided at the beginning of the paper.
  • Readers are encouraged to check the link for the latest information.
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Article Synopsis
  • - This study focused on pregnant women using antiepileptic drugs and their intake of folic acid, revealing that 83.3% had inadequate levels of folic acid consumption.
  • - Participants were divided into two groups based on when they began folic acid supplementation, with various factors like younger age and unplanned pregnancies contributing to inadequate intake.
  • - The findings suggest that planned pregnancies significantly influence folic acid intake, highlighting the need for healthcare professionals to educate women about the importance of folic acid and planned pregnancies when using antiepileptic medications.
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Purpose: To evaluate the prevalence and patterns of prescriptions of antiepileptic drugs (AEDs) to prenatal and postpartum women in Japan using a large administrative database.

Methods: The dates of pregnancy onset and delivery were estimated using published algorithms and infant birth months. The prevalence of prescribed AEDs, the maximum dose of some AEDs, and the frequency of potential combination therapy with AEDs were evaluated for the 180 days before pregnancy onset, during pregnancy, and at 180-day postpartum.

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Objectives: We investigated the effectiveness of clopidogrel loading (CL) treatment compared with usual clopidogrel non-loading (NL) treatment for acute ischemic cerebrovascular disease.

Methods: We screened consecutive 1072 patients with ischemic cerebrovascular disease within 48 hours of symptom onset admitted to our hospital. Eligible patients were divided into the CL group (300 mg on day 1, followed by 50-75 mg once daily) and NL group (50-75 mg once daily).

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We report novel compound heterozygous mutations of the UDP-N-acetylglucosamine-2-epimerase and N-acetylmannosamine kinase (GNE) gene, c.302G>A (p.R101H) and c.

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We report the use of intravenous tissue plasminogen activator (t-PA) therapy in a 38-year-old patient who was later diagnosed with unilateral moyamoya syndrome. The patient had a sudden onset of unconsciousness, vomiting, dysarthria, and tetraparesis. A neurologic examination revealed consciousness disturbance, right central facial nerve palsy, dysarthria, and tetraparesis with bilateral exotropia and horizontal gaze palsy.

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We report 2 cases that were considered to be neuro-Sweet disease. They initially manifested with meningoencephalitis and no skin lesions, and rapidly improved with corticosteroid therapy. In both cases, patients complained of meningitic symptoms such as fever and headache, and HLA-B54 and -Cw1 turned out to be positive over the clinical course.

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