Publications by Yasuhiro Tai

Publications by authors named "Yasuhiro Tai"

Gen Thorac Cardiovasc Surg

January 2025

This study investigated the effects of perioperative inhaled tiotropium on patients with COPD undergoing esophagectomy, focusing on pneumonia risk and pulmonary function.
32 patients were randomly assigned to either a control group with conventional management or an intervention group receiving tiotropium inhalation before and after their surgery.
While the incidence of pneumonia was similar in both groups, the patients using tiotropium showed improved pulmonary function and exercise capacity, leading to less deterioration post-surgery.

- Yasuhiro Tai's research primarily focuses on developing and refining methods for ensuring the sterility of drug manufacturing processes, particularly through the use of helium leak testing in sealed packaging systems.
- The studies emphasize the relationship between helium leaks and the integrity of packaging, specifically investigating how pinhole diameter affects sterility assurance in "double-bag" kit systems for drug infusion.
- The findings have contributed to establishing more efficient, reliable techniques for maintaining aseptic conditions during the transport and storage of pharmaceuticals, which is crucial for the safety and efficacy of drug products.