Publications by authors named "Yasuhiro Mihashi"
Article Synopsis
- - This study investigates the effectiveness of the minute ventilation-carbon dioxide production slope compared to the oxygen uptake efficiency slope in assessing exercise efficiency in COPD patients.
- - The researchers analyzed data from 122 COPD patients across all GOLD stages, finding significant differences in exercise parameters between mild (GOLD I-II) and more severe (GOLD III-IV) groups.
- - Results showed that the minute ventilation-carbon dioxide production slope had a stronger correlation with key indicators of oxygen consumption than the oxygen uptake efficiency slope, particularly in severe cases of COPD with exertional hypoxemia.
Article Synopsis
- * The study compared clinical data from 29 NTM-PD patients and 12 control participants, finding that NTM-PD patients had lower peak oxygen uptake and correlated changes in oxygen consumption during exercise with ventilatory variables, imaging findings, and cardiac pressure gradients.
- * Results indicate that exertional oxygen consumption is linked to exercise tolerance and ventilatory efficiency in NTM-PD patients, highlighting the importance of tailoring rehabilitation programs to address their unique respiratory challenges like tachypnea and bronchiectasis.
Article Synopsis
- Researchers previously found that widening the larynx can enhance exercise tolerance in patients with COPD.
- A case study of a severe COPD patient revealed that leaning forward caused extended expiration time and significant laryngeal narrowing while not obstructing the trachea.
- The findings suggest that how body positioning affects airway function could play a crucial role in improving exercise tolerance for individuals with COPD.
Amikacin liposome inhalation suspension (ALIS) is a key drug for the treatment of refractory complex pulmonary disease (MAC-PD). Although cases of drug-induced interstitial lung disease (DIILD) by ALIS have been reported, its diagnosis is challenging due to overlapping existing pulmonary shadows, airway bleeding, exacerbation of underlying conditions, and the potential for various concurrent infections. A 72-year-old woman started treatment with ALIS for refractory MAC-PD.
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