Duloxetine-induced hyponatraemia in a patient with hypocortisolaemia.

Duloxetine-induced hyponatraemia is a known adverse effect that can lead to potentially life-threatening complications. In addition, hypocortisolaemia is associated with the development of hyponatraemia. Here, we report a case of severe hyponatraemia rapidly presenting after duloxetine treatment in a patient with hypocortisolaemia.

Effects of surface roughness of ceria-stabilized zirconia/alumina nanocomposite on the morphology and function of human gingival fibroblasts.

We evaluated the biological effects of implant abutments made from ceria-stabilized zirconia/alumina nanocomposite (Ce-TZP/AlO) with surface roughness variations using human gingival fibroblasts (HGF-1) in the transmucosal region. Two types of titanium (Ti) and Ce-TZP/AlO disks with different surface roughness profiles were prepared (Ra0.9 and Ra0.

Canagliflozin improves obesity and insulin resistance in a diabetic patient with Cushings disease undergoing postoperative steroid therapy: A case report.

A 47-year-old woman with diabetes treated with high-dose insulin was admitted to Mie University Hospital, Tsu, Japan, for screening of secondary diabetes mellitus and obesity. Laboratory tests and imaging studies were consistent with Cushing's disease (CD). The patient underwent trans-sphenoidal pituitary surgery.

Surface quality of yttria-stabilized tetragonal zirconia polycrystal in CAD/CAM milling, sintering, polishing and sandblasting processes.

This paper studied the surface quality (damage, morphology, and phase transformation) of yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) in CAD/CAM milling, and subsequent polishing, sintering and sandblasting processes applied in dental restorations. X-ray diffraction and scanning electron microscopy (SEM) were used to scan all processed surfaces to determine phase transformations and analyse surface damage morphology, respectively. The average surface roughness (R) and maximum roughness (R) for all processed surfaces were measured using desk-top SEM-assisted morphology analytical software.

A case of type 2 diabetes mellitus with metformin-associated lactic acidosis initially presenting the appearance of a sulfonylurea-related hypoglycemic attack.

Case: A 64-year-old Japanese woman with diabetes mellitus was admitted for hypoglycemia. Her diabetes had been under good control with glimepiride, voglibose, exenatide, and metformin for a few years. Although overt proteinuria was observed, the serum creatinine values were within normal range during the routine outpatient follow-up.

Bending properties of Ce-TZP/A nanocomposite clasps for removable partial dentures.

Purpose: Ceria-stabilized zirconia/alumina nanocomposite (Ce-TZP/A) has excellent fracture toughness and bending strength that could be useful for partial denture framework application. The aim of this study was to investigate the effects of three-dimensional (3D) geometry on the bending and fatigue properties of a model simulation of Ce-TZP/A clasps.

Materials And Methods: Half oval-shaped Ce-TZP/A rods were prepared in six 3D designs.

Compatibility of Ce-TZP/Al2O3 nanocomposite frameworks and veneering porcelains.

The aim of this study was to examine the compatibility of Ce-TZP/Al2O3 nanocomposite (CTA) frameworks and veneering porcelains using the Schwickerath crack initiation test and clarify the effects on debonding/crack initiation strength (DIS) of both surface pretreatment (include heat treatment) of the frameworks, type of veneering porcelain varying the coefficient of thermal expansion (CTE), and surface roughness of the frameworks. The surfaces of Ce-TZP/Al2O3 plates were mechanically treated and followed by post-heat treatment. The liner and body porcelains were built up and fired according to the manufacturer's instructions.

Properties of experimental titanium cast investment mixing with water reducing agent solution.

This study aimed to develop a dental investment for titanium casting. ZrO(2) and Al(2)O(3) were selected as refractory materials to prepare three investments (Codes: A-C) according to the quantity of Zr. Al(2)O(3) cement was used as a binder at a ratio of 15%, they were mixed with special mixing liquid.

Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat.

Background: It is difficult to study the mechanisms of the metabolic syndrome in humans due to the heterogeneous genetic background and lifestyle. The present study investigated changes in the gene and protein profiles in an animal model of the metabolic syndrome to identify the molecular targets associated with the pathogenesis and progression of obesity related to the metabolic syndrome.

Methods: We extracted mRNAs and proteins from the liver tissues of 6- and 25-week-old spontaneously hypertensive/NIH -corpulent rat SHR/NDmcr-cp (CP), SHR/Lean (Lean) and Wistar Kyoto rats (WKY) and performed microarray analysis and two-dimensional difference in gel electrophoresis (2D-DIGE) linked to a matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry (MALDI-TOF/TOF MS).

Soda-lime glass as a binder in reusable experimental investment for dental castings.

In this study, different glasses were investigated to improve reusable investments. Borosilicate glass (BSG) powder and soda-lime glass (SLG) powder were prepared by milling broken beakers and microscope slides, respectively, and used in experimental investments (I-BSG, I-SLG) by blending glass powder (10 wt%) with cristobalite (90 wt%). Some properties and casting fits were evaluated with commercial gypsum-bonded investment as the control.

Novel fabrication method for zirconia restorations: bonding strength of machinable ceramic to zirconia with resin cements.

A novel method was developed to fabricate all-ceramic restorations which comprised CAD/CAM-fabricated machinable ceramic bonded to CAD/CAM-fabricated zirconia framework using resin cement. The feasibility of this fabrication method was assessed in this study by investigating the bonding strength of a machinable ceramic to zirconia. A machinable ceramic was bonded to a zirconia plate using three kinds of resin cements: ResiCem (RE), Panavia (PA), and Multilink (ML).

Combination treatment of tribochemical treatment and phosphoric acid ester monomer of zirconia ceramics enhances the bonding durability of resin-based luting cements.

The aim of the present study was to evaluate the bonding durability of resin-based luting cement to partially stabilized tetragonal zirconia (Y-TZP) achieved by combination treatment of tribochemical (TBC) treatment and two different phosphate acid ester monomers. Two phosphate acid ester monomers (EP: Epricord opaque primer, AZ: AZ primer) were applied to each surface modification followed by application of resin-based luting cement (Rely-X ARC). Bonding specimens were placed in deionized water at 37 degrees C and stored for 24 h.

A review of dental CAD/CAM: current status and future perspectives from 20 years of experience.

In this article, we review the recent history of the development of dental CAD/CAM systems for the fabrication of crowns and fixed partial dentures (FPDs), based on our 20 years of experience in this field. The current status of commercial dental CAD/CAM systems developed around the world is evaluated, with particular focus on the field of ceramic crowns and FPDs. Finally, we discuss the future perspectives applicable to dental CAD/CAM.

Effect of sintering on the marginal and internal fit of CAD/CAM-fabricated zirconia frameworks.

The aim of this study was to investigate the effect of post-machining sintering on marginal and internal fit of CAD/CAM-fabricated zirconia frameworks. Single crown copings (A: abutment), three-unit bridge frameworks (APA, P: pontic), four-unit bridge frameworks (APPA), and five-unit bridge frameworks (A1P1A2P2A3) were fabricated with raw-stage zirconia blanks using a commercial CAD/CAM system (KATANA, Noritake Dental Supply Co. Ltd.

Bonding strength of resin cement to silicate glass ceramics for dental CAD/CAM systems is enhanced by combination treatment of the bonding surface.

To increase the bond strength of CAD/CAM-fabricated, leucite-reinforced glass ceramics with a resin cement, the effects of the following were investigated: surface modification by tribochemical (TBC) treatment, followed by combined application of a silane coupling agent and a functional monomer as a primer. Bond strength was evaluated by a shear bond test. It was found that a silane coupling agent was useful for all the surfaces, particularly for the TBC-treated surface.

Experimental binder-free investments reused to cast dental precious alloys.

This study aimed to develop reusable dental investments. SiO2 and MgO were selected as refractory materials to prepare three types of investment (coded as 60S-40M, 80S-20M, 100S) with 40, 20, and 0 wt% of MgO. Each type of investment was reused twice.

Novel method for titanium crown casting using a combination of wax patterns fabricated by a CAD/CAM system and a non-expanded investment.

Objectives: For titanium casting, most commercial investments for titanium recommend casting at a low mold temperature to reduce oxidation. However, the thermal expansion values of the molds at low casting temperatures may be insufficient. The purpose of the current study was to investigate the possibility of obtaining accurate titanium crown casts using wax pattern fabricated by a CAD/CAM system with a non-expanded mold.

Fracture toughness measurement of dental ceramics using the indentation fracture method with different formulas.

This study examined fracture toughness (KIC) measurements obtained using the indentation fracture (IF) method with a view to improving their reliability. The KIC values of five dental ceramics were measured using the IF method with five different formulas, and the single-edge precracked beam (SEPB) method was used as a control. The elastic moduli of the dental ceramics were evaluated by dynamic hardness test.

Machining accuracy of CAD/CAM ceramic crowns fabricated with repeated machining using the same diamond bur.

The purpose of this study was to investigate the effect of repeated machining up to 51 times using the same diamond bur on machining accuracy of inner and outer surfaces of CAD/CAM (computer-aided designing and computer-aided manufacturing) machined ceramic crowns. The surface topography of machined crowns was examined using photographs. It was found that machining accuracy was not affected by the number of machining times.

Recycling of used commercial phosphate-bonded investments with additional mono-ammonium phosphate.

Industrial waste is on the increase, resulting in severe environmental contamination. Against this background, this study sought to investigate the possibility of recycling used phosphate-bonded investments. Commercial phosphate-bonded investment was mixed and heated according to manufacturer's instructions, then powdered with a ball mill machine to be used as recycled investment (Code: R).

Durability of tungsten carbide burs for the fabrication of titanium crowns using dental CAD/CAM.

The purpose of this study was to evaluate the durability of tungsten carbide burs for the fabrication of titanium crowns using two dental CAD/CAM systems (DECSY, Digital Process, Japan and Cadim, Advance, Japan). A tungsten carbide bur in each system was examined and used without fracture to fabricate 51 titanium crowns. For both systems tiny chips were found on the bur blade at the 11th machining.