Publications by authors named "Yasuhiko Gotoh"

Article Synopsis
  • * The BDOs exhibited various morphological forms and genetic mutations (KRAS at 15% and TP53 at 55%), similar to those from surgical samples.
  • * Three methods (repeat passage, xenografting, MDM2 inhibitor selection) effectively enriched cancer organoids by filtering out noncancerous cells, highlighting BDOs’ potential role in personalized medicine despite some limitations.
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There is no established treatment for rectal varices. Although endoscopic cyanoacrylate (N-butyl 2-cyanoacrylate) injection therapy is the standard treatment for gastric varices, there are few reports of its use for rectal varices. We present a case of rectal varix that was successfully treated with endoscopic cyanoacrylate injection therapy.

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Proton pump inhibitors (PPIs) have been the first line treatment for gastroesophageal reflux disease (GERD). The aim of this study was to evaluate the efficacy of vonoprazan (VPZ), a potassium-competitive acid blocker for reflux esophagitis (RE), nonerosive reflux disease (NERD), and PPI-resistant GERD patients.An open-label, single-center, observational study in our hospital was performed from August 2016 to August 2017.

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Background And Aim: Endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS) is often indicated for advanced stage patients. Therefore it is important to prevent adverse events associated with EUS-HGS procedures and obtain long stent patency. EUS-guided antegrade stenting (AS) has been developed as an advanced technique.

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