Publications by authors named "Yasue Takeuchi"
Article Synopsis
- Chronic hepatitis B and C are major global health concerns that lead to serious liver issues, including cirrhosis and cancer, but Japan has implemented effective testing and treatment measures for early liver cancer detection.
- In 2018, Japan established a policy for medical expense subsidies and research aimed at helping patients with advanced liver disease, which has successfully increased access to treatment and the number of beneficiaries.
- Despite these advancements, there are still inconsistencies in support across different regions, highlighting the need for better public awareness and improved collaboration within the healthcare system to assist patients effectively.
Nationwide awareness-raising program for viral hepatitis in Japan: the "" project.
Glob Health Med
October 2021
Chronic viral hepatitis is one of the most widespread infectious diseases in Japan. In the 2009 financial year, the Japanese government enacted the Basic Act on Hepatitis Measures, followed by the Basic Guidelines for Promotion of Control Measures for Hepatitis 2 years later. The guidelines emphasize the importance of provision and dissemination of accurate information on viral hepatitis and public awareness-raising.
View Article and Find Full Text PDFBackground: Hepatitis B virus (HBV) X (HBx) protein is associated with hepatocellular carcinogenesis via the induction of malignant transformation and mitochondrial dysfunction. However, the association between HBx and histone methyltransferase in carcinogenesis has not been fully clarified. In the current study, we analyzed the association between HBx and the histone methyltransferase suppressor of variegation 3-9 homolog 1 (SUV39h1) using HBV replication models.
View Article and Find Full Text PDFWe report a 46-year-old male patient with functional liver damage due to hepatitis B virus infection. A 12 cm hepatocellular carcinoma (HCC) in the left lobe and portal venous tumor thrombosis (PVTT) with vp4 (portal vein tumor thrombosis in the main trunk) were detected by computed tomography (CT). He underwent hepatic arterial infusion chemotherapy (HAIC) with cisplatin 100 mg for HCC and received radiation therapy (39 Gy/13 Fr) for PVTT with vp4.
View Article and Find Full Text PDFAim: Treatment with all-oral direct-acting antiviral agents (DAAs) elbasvir/grazoprevir (EBR/GZR) is associated with high sustained virologic response (SVR). The aim of this study was to evaluate the safety and treatment efficacy of EBR/GZR in hepatitis C virus (HCV)-infected patients.
Methods: This retrospective cohort study included 147 consecutive patients with chronic HCV genotype 1b infection who were treated with EBR (50 mg) plus GZR (100 mg) once daily for 12 weeks.