Taxane-based regimens as adjuvant treatment for breast cancer: a retrospective study in egyptian cancer patients.

Background: To evaluate the impact of adding taxanes to anthracycline-based regimens in the adjuvant setting in localized young female breast cancer patients on the overall survival (OS) and the disease free survival (DFS).

Materials And Methods: This retrospective study included all female breast cancer patients who were candidates for adjuvant chemotherapy presenting to Kasr Al Ainy centre of clinical oncology and Cairo oncology centre (Cairo Cure) in the period from January 2005 till December 2010.

Results: Our study included 865 patients, 732 of whom received anthracycline based regimens and 133 taxane based regimens.