Genotoxicity linked to occupational exposure in uranium mine workers: Granzyme B and apoptotic changes.

Background: Uranium mining and processing are an ancient occupation, recognized as being grueling and accountable for injury and disease. Uranium (U) is a radioactive heavy metal used in many industrial applications. It increases the micronuclei frequencies as well as chromosomal aberration and sister chromatid exchange in peripheral blood lymphocytes.

Effect of follicular diameter at the time of ovulation triggering on pregnancy outcomes during intrauterine insemination.

Objective: To compare pregnancy outcomes when triggering ovulation at different follicle sizes during intrauterine insemination (IUI) cycles.

Methods: A prospective observational study was undertaken at two collaborative fertility centers in Saudi Arabia between January 2014 and May 2016. Women of any age were enrolled if they met inclusion criteria: primary, secondary, or unexplained infertility (≥1 year); day-2 follicle-stimulating hormone less than 12 IU/mL; normal prolactin, thyroid function, and uterine cavity; at least one patent tube; and a male partner with normal semen count and motility.

Development and validation of the Arabic pediatric voice handicap index.

Background And Objective: Voice problems negatively affect how children are perceived both by adults and by their peers. Although voice disorders are common in the pediatric population, there is still a lack of information available to clinicians regarding evaluation and treatment of pediatric voice disorders. The purpose of the present study was to develop an Arabic version of pediatric VHI and to test its validity and reliability.

Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock.

Background: Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may cause death. Adrenaline is recommended as the initial treatment of choice for anaphylaxis.

Objectives: To assess the benefits and harms of adrenaline (epinephrine) in the treatment of anaphylaxis.