Publications by authors named "Yasmine Benhadid-Brahmi"
Article Synopsis
- Malassezia spp. are naturally found in various parts of the human body, including the skin and gut, but are challenging to culture, leading to the development of molecular methods like pan-M-qPCR for detection.
- The study tested this method on 361 clinical samples from different patient groups to assess Malassezia levels, revealing higher quantities in seborrheic dermatitis and burned patients compared to healthy individuals.
- Results showed that the pan-M-qPCR is effective for quantifying Malassezia, highlighting its higher presence in specific areas of the body and its potential as a valuable tool for studying this fungal genus in human microbiomes.
Article Synopsis
- Cryptococcal antigen (CrAg) is a marker found in the fluids of patients with cryptococcal infections, and various testing methods like CALAS and LFA are used to detect it, including commercial kits like CryptoPS and CrAg LFA.
- In a 3-year study involving 43 serum samples, the CryptoPS test showed a high rate of false positives, indicating that patients without cryptococcal infections often tested positive, suggesting the presence of interfering substances in the serum.
- A simple pretreatment method (incubation and centrifugation) was effective in reducing false positives, though it slightly affected the sensitivity of the test for some patients with actual cryptococcal disease.
COVID-19-associated mold infections have been increasingly reported, and the main entity is COVID-19-associated aspergillosis (CAPA). Similarly, COVID-19-associated mucormycosis has been reported in hematology, and its prevalence is high and has been increasing in the diabetic population in India during the third COVID-19 pandemic wave. Simultaneous infection with Mucorales and Aspergillus is rare and even rarer during COVID-19.
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