Safety and efficacy of three alternative regimens against relapsing Plasmodium vivax malaria in glucose 6-phosphate dehydrogenase deficient patients in the Brazilian Amazon (ALTPRIM).

Background: Daily primaquine-induced hemolysis is a common cause of complications during Plasmodium vivax malaria treatment in individuals with glucose 6-phosphate dehydrogenase deficiency (G6PDd). Alternative regimens balancing safety and efficacy are needed.

Methods: G6PDd participants with P.

Franciscana dolphins, Pontoporia blainvillei, as environmental sentinels of the world's largest mining disaster: Temporal trends for organohalogen compounds and their consequences for an endangered population.

On November 5th, 2015, the Fundão dam collapsed in Minas Gerais, southeastern Brazil, releasing millions of cubic meters of mud containing mining residue into the Doce River. Two weeks later, the mud arrived to the marine environment, triggering changes in franciscana dolphin habitat, Pontoporia blainvillei, from Franciscana Management Area Ia. This is an isolated population of the most endangered cetacean species in the South Atlantic Ocean.

Silorane-based Composite Resin Restorations Are Not Better than Conventional Composites - A Meta-Analysis of Clinical Studies.

Purpose: To perform a systematic review of the clinical performance of a low polymerization shrinkage, siloranebased composite (SBC) compared with a methacrylate-based composite (MBC) in posterior restorations.

Materials And Methods: Electronic databases were searched: PubMed, Scopus, Bireme, Science Direct, Web of Science, ClinicalTrials.gov and OpenGrey.