Publications by authors named "Yasmin Riesinger"
Stem Cell Res
January 2019
Article Synopsis
- Alzheimer's Disease (AD) is a leading cause of dementia among older adults, and research indicates that neurons made from patient-derived induced pluripotent stem cells (iPSCs) can mimic key features of the disease, like tau phosphorylation and amyloid beta deposition.
- Researchers created a group of iPSC lines from two sporadic AD patients and three healthy controls, all derived from skin cells (dermal fibroblasts).
- The produced iPSC lines displayed normal chromosome patterns, expressed stem cell markers, and successfully differentiated into cells from all three germ layers (endoderm, mesoderm, and ectoderm).
