Failure of multiple therapies in the treatment of a type 1 diabetic patient with insulin allergy: a case report.

Objective: To describe the clinical manifestations of insulin allergy and explain a systematic management approach.

Methods: We present the clinical, laboratory, and pathologic findings of a type 1 diabetic patient with allergy to subcutaneous insulin and briefly review the related literature.

Results: An 18-year old woman with type 1 diabetes mellitus had an insulin allergy and developed subcutaneous nodules after insulin administration.