Publications by authors named "Yasmeen Choudhri"

Article Synopsis
  • Clinicians and patients often need to decide whether to continue or stop taking statins, and this study investigates the effects of such decisions on health outcomes like mortality and quality of life.* -
  • Researchers conducted a systematic review of various studies on statin use and found that discontinuing statins might be linked to a higher risk of overall and cardiovascular mortality as well as cardiovascular events, especially in non-randomized studies.* -
  • The only randomized controlled trial included had limited findings, showing no significant difference in short-term mortality for those who stopped statins, while results for older adults (≥75 years) were consistent with the overall trends observed.*
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Objective: Interindividual variability in the clinical progression of COVID-19 may be explained by host genetics. Emerging literature supports a potential inherited predisposition to severe forms of COVID-19. Demographic and inflammatory characteristics of COVID-19 suggest that acquired hematologic mutations leading to clonal hematopoiesis (CH) may further increase vulnerability to adverse sequelae.

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Background: Nighttime and weekends in hospital and intensive care unit (ICU) contexts are thought to present a greater risk for adverse events than daytime admissions. Although some studies exist comparing admission time with patient outcomes, the results are contradictory. No studies currently exist comparing costs with the time of admission.

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Article Synopsis
  • Healthcare expenditures in ICUs are high, and this study focuses on high-cost users who make up a significant portion of these costs, assessing their health outcomes and spending patterns.
  • A retrospective study of ICU patients in Ontario identified 37,006 high-cost users, characterized by older age, higher comorbidities, and significantly longer ICU stays (22.4 days vs. 5.56 days for non-high-cost users).
  • Despite having lower in-hospital mortality rates, high-cost users had total healthcare costs that were five times greater than their non-high-cost counterparts, highlighting the need for further research to understand and potentially mitigate these expenses.
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