Insights into the biogenic production of nanocomposites of NiO-chitosan for wastewater remediation.

In our study, we have tried to enhance the biological qualities of nickel oxide nanoparticles and nanocomposites which were prepared using the extract of Aegle marmelos tree leaves and chitosan biopolymer. For in-depth study of the fabricated samples, numerous physiochemical approaches were utilized. The analysis used consists of field emission scanning electron microscopy with energy dispersive X-ray analysis and photoluminescence, X-ray diffraction, UV-visible spectroscopy, and Fourier transform infrared spectroscopy.

NiO/PANI nanocomposite doped carbon paste as electrode for long-term stable and highly efficient perovskite solar cells.

Carbon-based perovskite solar cells (PSCs) have emerged as a hopeful alternative in the realm of photovoltaics. They are considered promising due to their affordability, remarkable durability in humid environments, and impressive electrical conductivity. One approach to address the cost issue is to use affordable counter electrodes in PSCs that do not require organic hole transport materials (HTMs).

Magnetic nanocomposite based on chitosan-gelatin hydrogel embedded with copper oxide nanoparticles: A novel and promising catalyst for the synthesis of polyhydroquinoline derivatives.

Nanocatalysts are vital in several domains, such as chemical processes, energy generation, energy preservation, and environmental pollution mitigation. An experimental study was conducted at room temperature to evaluate the catalytic activity of the new gelatin-chitosan hydrogel/CuO/FeO nanocomposite in the asymmetric Hantzsch reaction. All components of the nanocomposite exhibit a synergistic effect as a Lewis acid, promote the reaction.

A versatile magnetic nanocomposite based on cellulose-cyclodextrin hydrogel embedded with graphene oxide and CuO nanoparticles for catalytic application.

The study focused on creating a novel and environmentally friendly nanocatalyst using cellulose (Cell), β-Cyclodextrin (BCD), graphene oxide (GO), CuO, and FeO.The nanocatalyst was prepared by embedding GO and CuO into Cell-BCD hydrogel, followed by the in-situ preparation of FeO magnetic nanoparticles to magnetize the nanocomposite. The effectiveness of this nanocatalyst was evaluated in the one-pot, three-component symmetric Hantzsch reaction for synthesizing 1,4-dihydropyridine derivatives with high yield under mild conditions.

A comprehension of signaling pathways and drug resistance; an insight into the correlation between microRNAs and cancer.

Despite the development of numerous therapies, cancer remains an incurable disease due to various factors, including drug resistance produced by cancer cells. MicroRNAs (miRNAs) regulate different target genes involved in biological and pathological processes, including cancer, through post-transcriptional mechanisms. The development of drug resistance in cancer treatment is a significant barrier because it decreases drug uptake, cellular transport, and changes in proteins involved in cell proliferation, survival, and apoptotic pathways.

Oxidative stress affects the beginning of the growth of cancer cells through a variety of routes.

Oxidative stress is a physiological condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the cell's antioxidant defense system. ROS are highly reactive molecules that can cause damage to cellular structures such as DNA, proteins, and lipids. the regulation of ROS levels and the antioxidant defense system is crucial for cancer prevention and treatment.

LncRNA PVT1: as a therapeutic target for breast cancer.

A significant number of women are identified with breast cancer (BC) every year, making it among the most prevalent malignancies and one of the leading causes of mortality globally. Despite significant progress in understanding BC pathogenesis and treatment options, there is still a need to identify new therapeutic targets and develop more effective treatments. LncRNAs have been discovered as biomarkers and a promising target for various cancers, including BC.

CDKN2B-AS1 as a novel therapeutic target in cancer: Mechanism and clinical perspective.

Long non-coding RNAs (lncRNA) have been identified as essential components having considerable modulatory impactson biological activities through altering gene transcription, epigenetic changes, and protein translation. Cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1), a recently discovered lncRNA, was shown to be substantially elevated in various cancers.Furthermore, via modulation ofvarious signalingaxes, it is effectively connected to the control of critical cancer-associatedbiological pathways likecell proliferation, apoptosis, cell cycle, epithelial-mesenchymal transition(EMT), invasion, and migration.

Dermoscopy of topical steroid-dependent or damaged face: A cross-sectional study.

Background: Topical corticosteroid (TCS) abuse is rampant and results in steroid addiction labeled as topical steroid-dependent or damaged face (TSDF). Indian market is replete with triple combination creams containing TCS sold as over-the-counter products at low cost, luring people to use them without prescription. The resultant damage if detected late is irreversible and difficult to treat.