Metasurface-Coated Liquid Microlens for Super Resolution Imaging.

Inspired by metasurfaces' control over light fields, this study created a liquid microlens coated with a layer of Au@TiO, Core-Shell nanospheres. Utilizing the surface plasmon resonance (SPR) effect of Au@TiO, Core-Shell nanospheres, and the formation of photonic nanojets (PNJs), this study aimed to extend the imaging system's cutoff frequency, improve microlens focusing, enhance the capture capability of evanescent waves, and utilize nanospheres to improve the conversion of evanescent waves into propagating waves, thus boosting the liquid microlens's super-resolution capabilities. The finite difference time domain (FDTD) method analyzed the impact of parameters including nanosphere size, microlens sample contact width, and droplet's initial contact angle on super-resolution imaging.

Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages.

In this study, we investigated the signaling pathway involved in cyclooxygenase-2 (COX-2) expression caused by peptidoglycan (PGN), a cell wall component of the Gram-positive bacterium Staphylococcus aureus, in RAW 264.7 macrophages. PGN caused dose- and time-dependent increases in COX-2 expression, which was attenuated by a Ras inhibitor (manumycin A), a Raf-1 inhibitor (GW 5074), and an MEK inhibitor (PD 098059).