Structure-Based Design of Dual Bactericidal and Bacteria-Releasing Nanosurfaces.

Here, we report synergistic nanostructured surfaces combining bactericidal and bacteria-releasing properties. A polystyrene--poly(methyl methacrylate) (PS--PMMA) diblock copolymer is used to fabricate vertically oriented cylindrical PS structures ("PS nanopillars") on silicon substrates. The results demonstrate that the PS nanopillars (with a height of about 10 nm, size of about 50 nm, and spacing of about 70 nm) exhibit highly effective bactericidal and bacteria-releasing properties ("dual properties") against for at least 36 h of immersion in an solution.