Publications by authors named "Yash Shah"

Gastric cancer remains a major global health concern with high incidence and mortality rates, particularly in East Asia. Patients often have poor outcomes due to limited treatment efficacy. Zolbetuximab, a monoclonal antibody targeting claudin 18.

View Article and Find Full Text PDF

Computational analysis of countercurrent flows in packed absorption columns, often used in solvent-based post-combustion carbon capture systems (CCSs), is challenging. Typically, computational fluid dynamics (CFD) approaches are used to simulate the interactions between a solvent, gas, and column's packing geometry while accounting for the thermodynamics, kinetics, heat, and mass transfer effects of the absorption process. These simulations can then be used explain a column's hydrodynamic characteristics and evaluate its CO-capture efficiency.

View Article and Find Full Text PDF
Article Synopsis
  • Vasculitides cause inflammation of blood vessel walls and mesenteric vasculitis (MV) specifically affects the blood vessels in the gastrointestinal tract, often linked to systemic inflammation but can also occur alone.
  • Common symptoms of MV include nausea, abdominal pain, diarrhea, and rectal bleeding, which complicate diagnosis and can lead to serious health risks if missed.
  • The review highlights the need for timely diagnosis and appropriate treatment to avoid unnecessary surgeries, while also pointing out challenges in distinguishing MV from similar gastrointestinal conditions and the lack of clear diagnostic criteria in existing literature.
View Article and Find Full Text PDF

Introduction: Health insurance is a key instrument for a health system on its path to achieving universal health coverage (UHC) and protects individuals from catastrophic health expenditures, especially in health emergencies. However, there are other dimensions to care access beyond financial accessibility. In this study, we assess the geographical accessibility of comprehensive emergency obstetric care (CEmOC) within the Lagos State Health Insurance Scheme.

View Article and Find Full Text PDF

Introduction: Patients seek support from online resources when facing a troubling urologic cancer diagnosis. Physician-written resources exceed the recommended 6-8th grade reading level, creating confusion and driving patients towards unregulated online materials like AI chatbots. We aim to compare the readability and quality of patient education on ChatGPT against Epic and Urology Care Foundation (UCF).

View Article and Find Full Text PDF
Article Synopsis
  • A study aimed to explore the prevalence of penile fractures (PF) in men with Ehlers-Danlos Syndrome (EDS) and Marfan Syndrome (MFS), revealing that these patients have significantly higher rates of PF compared to disease-free controls.
  • The research analyzed a large database over 30 years, finding that men with EDS had a prevalence ratio of 30.18 and those with MFS had a ratio of 23.4 for PF.
  • While the study highlights an important link between connective tissue diseases and sexual health issues, it is limited by its reliance on claims data, which lacks finer details on disease progression and complications.
View Article and Find Full Text PDF
Article Synopsis
  • - Chronic kidney disease (CKD) is linked to a higher risk of serious complications after major surgeries, with this study specifically looking at 30-day outcomes across various surgical specialties.
  • - Analyzed data from over 1.9 million patients revealed that those with advanced CKD (stage 5) faced significantly greater odds of major complications, including death, unplanned surgeries, and cardiac issues compared to patients with better kidney function (stage 1).
  • - The findings emphasize the detrimental effects of CKD on surgical recovery, highlighting the need for careful preoperative assessment in patients with compromised kidney function.
View Article and Find Full Text PDF

Introduction: Placing ureteral stents at the ureteroileal anastomosis for radical cystectomy with ileal conduit (RCIC) has long been common practice. Recently, some providers have begun omitting stents. We sought to investigate differences in perioperative and 30-day outcomes between patients who underwent RCIC with and without stents placed at the ureteroileal anastomosis.

View Article and Find Full Text PDF

Pancreatic cancer is a rare but lethal cancer due to its biologically aggressive nature, advanced stage at the time of diagnosis, and poor response to oncologic therapies. The risk of pancreatic cancer is significantly higher to 5% in certain high-risk individuals with inherited genetic susceptibility. Screening for pancreatic cancer in these individuals from high-risk groups can help with the early detection of pancreatic cancer as well as the detection of precursor lesions leading to early surgical resection and improved overall outcomes.

View Article and Find Full Text PDF

Background: The benefits of achieving optimal cardiovascular health (CVH) through Life's Simple 7 (LS7) are well-documented across diverse populations. In this study, we assess the updated metrics, Life's Essential 8 (LE8), and their association with long-term cardiovascular disease (CVD) outcomes and mortality.

Methods: We conducted a comprehensive systematic review, searching PubMed, Google Scholar, Cochrane Library, and ScienceDirect from January 2022 until June 2024, focusing on studies that specifically assessed the impact of LE8 on CVH.

View Article and Find Full Text PDF

Colorectal cancer (CRC) has the highest mortality rate among men and is the second highest among women under fifty, with incidence and mortality rates rising in younger populations. Studies indicate that up to one-third of patients diagnosed before fifty have a family history or genetic factors, highlighting the need for earlier screening. Contrariwise, diagnosis in healthy subjects through screening strategies enables early-stage detection of the tumor and better clinical outcomes.

View Article and Find Full Text PDF

Background: A large body of evidence connects access to greenspace with substantial benefits to physical and mental health. In urban settings where access to greenspace can be limited, park access and use have been associated with higher levels of physical activity, improved physical health, and lower levels of markers of mental distress. Despite the potential health benefits of urban parks, little is known about how park usage varies across locations (between or within cities) or over time.

View Article and Find Full Text PDF
Article Synopsis
  • Most routine endoscopic procedures use sedation for patient comfort, with Propofol, benzodiazepines, and opioids being popular choices, but Remimazolam is emerging as a new option since its FDA approval in July 2020.
  • Remimazolam is an ultra-short-acting benzodiazepine with favorable pharmacological properties, showing non-inferior efficacy compared to Propofol while having fewer side effects like hemodynamic instability and respiratory depression.
  • This review explores Remimazolam's characteristics, effectiveness, and safety, suggesting it could be a safer and more efficient alternative for procedural sedation in gastrointestinal endoscopy.
View Article and Find Full Text PDF
Article Synopsis
  • - Groove pancreatitis (GP) is a rare type of chronic pancreatitis primarily affecting middle-aged men, with risk factors including excessive alcohol use, smoking, and pancreatic issues, leading to symptoms like severe abdominal pain and jaundice.
  • - Diagnosing GP is difficult due to its symptoms overlapping with other conditions, which can result in delayed treatment and increased health risks.
  • - The potential use of artificial intelligence in diagnostic imaging could help differentiate GP from pancreatic cancers, improving diagnosis and patient outcomes, as discussed in a comprehensive review of GP's causes, symptoms, and treatment options.
View Article and Find Full Text PDF

Introduction: In the 21st century, we are surrounded by plastic, disposal of which has a detrimental effect on the environment. Around 700 million plastic toothbrushes are sold which contributes to a large portion of plastic waste. To aid in the restoration of the environment, there is a need to replace plastic toothbrushes with recyclable toothbrushes.

View Article and Find Full Text PDF

The Quintuple Aim seeks to improve healthcare by addressing social determinants of health (SDOHs), which are responsible for 70-80% of medical outcomes. SDOH-related concerns have traditionally been addressed through referrals to social workers and community-based organizations (CBOs), but these pathways have had limited success in connecting patients with resources. Given that health inequity is expected to cost the United States nearly USD 300 billion by 2050, new artificial intelligence (AI) technology may aid providers in addressing SDOH.

View Article and Find Full Text PDF

Intermittent fasting (IF), characterized by alternating periods of fasting and unrestricted eating, typically within an 8-hour window or less each day, has gained significant attention as a possible dietary approach. While it is recognized for its metabolic advantages, like weight loss and enhanced glucose and insulin sensitivity, its effect on cardiovascular health remains a topic of mixed opinions. Recent findings suggest a potential downside, with reports indicating a concerning association: a 91 % higher risk of cardiovascular disease (CVD) mortality compared to eating spread across a 12- to 16-hour period.

View Article and Find Full Text PDF

Microwave couplers are used in large numbers in beamforming networks, and their miniaturization can lead to a significant size reduction in the overall phased array. While the miniaturization of 3 dB couplers in the transverse direction (width) has been given considerable attention in the literature, there is minimal to no information on reducing coupler length. This is because of the trade-off between aperture length, bandwidth and coupling strength.

View Article and Find Full Text PDF
Article Synopsis
  • Hepatitis A is usually a mild liver infection that resolves on its own, but can have rare complications like rhabdomyolysis, a condition that causes muscle breakdown.
  • A case is presented involving a 64-year-old man who experienced rhabdomyolysis and a rash due to hepatitis A and improved with conservative treatment.
  • The article stresses the need for healthcare providers to recognize atypical symptoms of hepatitis A, manage rare complications effectively, and consider vaccination and sanitation as preventative measures.
View Article and Find Full Text PDF

Background: Heart failure (HF) represents a substantial burden, impacting both health and financial domains. Despite the presence of evidence-based interventions for prevention and management, suboptimal care has been recognized as a critical contributor to adverse HF-related outcomes. We aim to analyze the impact of palliative care telehealth intervention compared to usual care in quality of life (QoL) and resource utilization of chronic HF patients.

View Article and Find Full Text PDF

Introduction Pre-eclampsia leads to long-lasting cardiovascular effects in women in the postpartum period, but prevalence and in-hospital adverse events of coronary artery disease (CAD) in women with pre-eclampsia are poorly understood. The prevalence, outcomes, and mortality risks identified in this study allow for possible routes of clinical intervention of CAD in women with pre-eclampsia. The purpose of this study was to determine the prevalence and outcomes of CAD in women diagnosed with pre-eclampsia compared to those with pre-eclampsia with no history of CAD.

View Article and Find Full Text PDF