Publications by authors named "Yaser Hadi Gholami"
Article Synopsis
- This study aims to create a new type of nanoparticle for better diagnostic imaging that can be used in both PET and MR scans without the need for chelators.
- Researchers successfully labeled a super-paramagnetic iron oxide nanoparticle with a radiotracer, achieving high radiochemical yield and purity, while confirming effective integration and contrast properties through imaging tests.
- The findings highlight that the developed nanoparticle could enhance image quality by providing improved spatial resolution and signal-to-noise ratio during concurrent PET-MR imaging, demonstrating its potential as a valuable diagnostic tool.
In cancer radiation therapy, dose enhancement by nanoparticles has to date been investigated only for external beam radiotherapy (EBRT). Here, we report on an in silico study of nanoparticle-enhanced radiation damage in the context of internal radionuclide therapy. We demonstrate the proof-of-principle that clinically relevant radiotherapeutic isotopes (i.
View Article and Find Full Text PDFToward Personalized Dosimetry with P Microparticle Therapy for Advanced Pancreatic Cancer.
Int J Radiat Oncol Biol Phys
November 2017
Purpose: To develop a Monte Carlo model for patient-specific dosimetry of P microparticle localized internal radionuclide therapy for advanced pancreatic cancer.
Methods And Materials: Spherical tumor geometries and a pancreatic phantom were modeled, as well as different 3-dimensional non-uniform clinical pancreatic geometries based on patient-specific ultrasound images. The dosimetry simulations modeled the dose distribution due to the energy spectrum of emitted beta particles.