Autologous cultured fibroblasts combined with plasma gel (Fibrogel) can be used as an injectable autologous soft tissue filler. Herein, we report the assessment of the long-term clinical efficacy and safety of Fibrogel for facial wrinkles. Ten healthy adults were treated for facial wrinkles with Fibrogel, an innovative autologous filler.
View Article and Find Full Text PDFIn recent years, autologous fibroblast injections or plasma gel filler applications have been used in the treatment of facial contour deformities. In this case report, we describe a new method of autologous filler material derived from cultured dermal fibroblast and plasma gel. The plasma gel, which is the bioskeleton of the filler, is prepared from the patient's plasma, which provides a dense environment for a three-dimensional configuration of dermal fibroblasts.
View Article and Find Full Text PDFJ Cosmet Dermatol
December 2016
Objective: This study assessed the safety and clinical efficacy of a low-fluence 1064-nm Q-switched neodymium-doped:yttrium aluminum garnet (QS-Nd:YAG) laser in the treatment of patients with melasma.
Methods: The study evaluated 34 melasma patients treated at a single institution using a 1064-nm QS-Nd:YAG laser. The laser parameters were 6 mm spot size and 2.
Granular parakeratosis (GP) is a benign disorder of keratinization presenting with unilateral or bilateral red to brown hyperkeratotic plaques and papules at the intertriginous areas. The first pediatric case of GP was reported in 2002, and only a few cases have been reported since. Although the exact etiology of GP is unknown, it is thought that certain environmental factors compromise the epidermal barrier and lead to proliferation and altered maturation of the epidermis in predisposed individuals.
View Article and Find Full Text PDFObjective: To assess the effectiveness of 10,600nm fractional CO2 laser for neck aging at one month and one year after treatment. Design/Setting/Participants/Measurement: Twenty patients underwent 10,600nm fractional CO2 laser treatment over the entire neck. Clinical features of the patients were classified according to Baker classification.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
March 2014
Objective: Postinflammatory hyperpigmentation is a reactive hypermelanosis of the skin that occurs as a consequence of an inflammatory process, such as acne, eczema, drug reactions, burns, chemical peelings, and laser applications. Although topical agents remain to be the first-line treatment of postinflammatory hyperpigmentation, treatment of recalcitrant cases is challenging. The Q-switched ruby laser, the low-dose Q-switched neodymium-doped yttrium aluminum garnet laser, and the fractional 1550nm erbium-doped fiber laser have been reported to improve postinflammatory hyperpigmentation.
View Article and Find Full Text PDFThe lifetime incidence of nail involvement in psoriatic patients is estimated to be 80-90%, and the nails can be affected in 10% to 55% of psoriatic patients. Psoriasis may also solely involve the nails, without any other skin findings, in which the treatment can be more challenging. Nail psoriasis may lead to considerable impairment in quality of life due to aesthetic concerns and more importantly limitations in daily activities resulting from the associated pain, which may be overlooked by the physicians.
View Article and Find Full Text PDFCase Rep Dermatol Med
December 2012
Basal cell carcinoma (BCC) is the most common malignancy of the skin. It is most frequently seen on the sun-exposed areas of the head and neck region. Occurrence of BCC on the nipple is extremely rare, though the number of the reported cases has been increasing steadily.
View Article and Find Full Text PDFBackground: The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.
Objectives: To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.
Methods: Psoriatic nails of five patients were treated using PDL (595 nm) once monthly for 3 months.
Background: The surgical treatments for pilonidal sinus disease often result in recurrences, and the patients risk requiring multiple surgical interventions.
Objective: To evaluate the role of alexandrite laser hair removal after surgery in pilonidal sinus disease.
Methods: Sixty patients who underwent surgical treatment of pilonidal sinus disease and were treated with a 755-nm alexandrite laser after surgery between 1999 and 2007 were examined retrospectively.