Publications by authors named "Yasemin Celik"

The removal of harmful chemicals and species from water, soil, and air is a major challenge in environmental remediation, and a wide range of materials have been studied in this regard. To identify the optimal material for particular applications, research is still ongoing. Polymer nanocomposites (PNCs), which combine the benefits of nanoparticles with polymers, an alternative to conventional materials, may open up new possibilities to overcome this difficulty.

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Acetaminophen is one of the most widely used over‑the‑counter drugs worldwide for the treatment of pain and fever. Although acetaminophen use is known to impair hippocampus‑related learning and memory, its effect on anxiety is not clear. Insulin‑like growth factor‑1 (IGF‑1) and matrix metalloproteinase‑2 (MMP2) are important for cellular survival, maintenance and tissue integrity.

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In various countries, polyethylene terephthalate (PET) represents one of the plastics with a very high recycling rate. Since currently there is no analytical method enabling direct distinction between recycled PET (rPET) and virgin PET (vPET), there are various attempts to differentiate these materials indirectly. One of these approaches claims that the recycling of PET leads to polymer chain degradation, which is reflected in changed thermal, mechanical and crystalline properties, and testing of these properties can therefore be used to distinguish rPET and vPET.

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Background: Colorectal cancer (CRC) screening rates are low in the general population and among health care providers. The aim of this study was to evaluate the CRC screening practices of general surgeons who provide specialized diagnostic testing and CRC treatment and to examine the CRC screening behaviors of their first-degree family members.

Methods: A cross-sectional survey was conducted among general surgeons who attended the 21st National Surgical Congress in Turkey held from April 11th to 15th, 2018.

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Objective: The aim of this study is to detect the overall evaluation of nursing students toward simulation makets throughout the practice education and to reveal their learning styles in relation to certain individual features.

Materials And Methods: The data were collected via questionnaires including students' evaluation toward simulation makets and "Kolb learning styles inventory." Participants included 103 male and female nursing students in Turkey.

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Objective: The aim of this study is to detect the overall evaluation of nursing students toward simulation markets throughout the practice education and to reveal their learning styles in relation to certain individual features.

Materials And Methods: The data were collected via questionnaires including students' evaluation toward simulation markets and "Kolb learning styles inventory." Participants included 103 male and female nursing students in Turkey.

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Objective: To investigate the role of N-terminal pro-brain natriuretic peptide and apelin in the assessment of right ventricular dysfunction in acute pulmonary embolism.

Methods: The prospective case-control study was conducted at Ondokuz Mayis University, Samsun, Turkey, from January 2008 to June 2009, and comprised adult patients with acute pulmonary embolism. A smaller group of healthy adults served as the control.

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The aim of the present study was to investigate the possible protective effects of boron, an antioxidant agent, against arsenic-induced oxidative stress in male and female rats. In total, 42 Wistar albino male and female rats were divided into three equal groups: The animals in the control group were given normal drinking water, the second group was given drinking water with 100 mg/L arsenic, and the third group was orally administered drinking water with 100 mg/kg boron together with arsenic. At the end of the 28-day experiment, arsenic increased lipid peroxidation and damage in the tissues of rats.

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Objective: The aim of this study is testing the value of H-FABP in the early diagnosis of ACS alone or with routinely used biomarkers such as myoglobin, CK-MB, and cTn I in patients who admitted to emergency department (ED) with complaint of chest pain and suspected acute coronary syndrome.

Material And Methods: This prospective and cross-sectional study was performed at the Emergency Department of University hospital between June 2009 and September 2010. Patients who were admitted with chest pain within first 48 hours and suspected ACS were enrolled to the study.

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Article Synopsis
  • The blood-brain barrier (BBB) protects the brain by preventing many substances from entering, using tight junctions and efflux transporters like P-glycoprotein (P-gp) to regulate what can pass through.
  • In brain metastases, the blood-tumor barrier (BTB) allows greater permeability but it's unclear how well P-gp functions in this compromised state.
  • Research in a mouse model shows that P-gp levels and activity at the BTB are comparable to the BBB, indicating that despite changes in integrity, efflux mechanisms like P-gp might still hinder drug delivery to brain tumors.
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Background/aims: Crohn's disease and ulcerative colitis are both chronic inflammatory disorders of the gastrointestinal tract, the main causes of which remain unknown. Crohn's disease and ulcerative colitis are characterized by cell-mediated immune response against the luminal bacteria. It is suggested that expression levels and function of P-glycoprotein, encoded by the MDR1 gene, are important for protection of the gut against xenobiotics and bacterial toxins.

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Purpose: The genetic susceptibility of people with certain NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene variants to inflammatory bowel disease is still under investigation. The aim of this study was to investigate polymorphisms in the NOD2/CARD15 (R702W, G908R, and 3020insC), NOD1/CARD4 (E266K, D372N), and ICAM-1 (G241R, K469E) genes, which are known to be associated with inflammation, in Turkish patients with inflammatory bowel disease and healthy control groups.

Methods: The genotypes of 70 patients with endoscopically and histopathologically diagnosed Crohn's disease (38 men, 32 women; mean age, 38.

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Objective: Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the bowel, the causes of which are not fully known. Ethnic differences in disease prevalence, familial aggregation of the disease and studies of twins provide the most important evidence to suggest that genetic factors play a role in the pathogenesis of inflammatory bowel disease (IBD). The aim of this study was to examine the allelic polymorphisms that can determine the immune response levels in tumor necrosis factor alpha (TNFalpha), interleukin-1beta (IL-1B), interleukin-1 receptor antagonist ( IL-1RN) and interleukin-10 (IL-10) genes and to investigate their roles in the inflammatory pathway in IBD.

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