Publications by authors named "Yaseen T"

Article Synopsis
  • Rectal varices are rare complications that occur due to portal hypertension, which can complicate diagnosis as they may resemble hemorrhoids in cirrhotic patients.
  • Distinguishing between rectal varices and hemorrhoids is crucial because they have different underlying causes and treatment options.
  • The text discusses key characteristics of both conditions and outlines important differences to aid in proper identification.
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  • The study presents a green method for synthesizing Iron oxide nanoparticles (IONPs) using the roots of the medicinal plant Sageretia thea, which is eco-friendly compared to traditional methods that rely on toxic chemicals.
  • Analytical tools like UV-Vis, FT-IR, XRD, EDX, and SEM confirmed the successful synthesis of IONPs, measuring an average size of 16.04 nm.
  • The IONPs exhibited significant biological activities, showcasing strong antibacterial and antifungal properties against various strains, along with notable cytotoxicity and anti-radical potentials (DPPH), indicating their potential for medical applications.
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  • The study investigates the link between vertical facial patterns and the structure of alveolar bone and teeth, which is important for effective orthodontic treatment planning.
  • Researchers analyzed 300 cone-beam computed tomography scans from orthodontic patients, focusing on alveolar bone thickness and the crown and root dimensions of maxillary anterior teeth across different facial types.
  • Results showed that short facial types had thicker alveolar bone compared to normal and long facial types, emphasizing the need to consider facial type during orthodontic planning.
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Zinc oxide nanoparticles have wide range biological, biomedical and environmental applications. However, traditional nanofabrication of ZnONPs uses various toxic chemicals and organic solvents which limit their bio-applications. To overcome this hurdle, Bauhinia variegata derived buds extract was utilized to fabricate ZnONPs.

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  • Pancreatobiliary lymphadenopathy (PBL) can be linked to various benign or malignant conditions, and endoscopic ultrasound (EUS) can help obtain tissue samples for diagnosis.
  • A study involving 87 patients revealed that the majority of cases were male (62.1%) with a mean age of 52, and the primary sites of enlarged lymph nodes were in the porta hepatis and peripancreatic areas.
  • The findings showed that most cases were due to metastatic adenocarcinoma for neoplastic reasons and tuberculosis for non-neoplastic reasons, with larger lymph node size and satisfactory on-site evaluation linked to better biopsy outcomes.
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  • Medicinal herbs have historically played a key role in treating various ailments, including cancer, with compounds like guggulsterone (GS) from the Commiphora mukul tree showing promise as an anticancer agent.
  • GS has been studied for its ability to induce cell death in cancer cells by targeting critical survival pathways such as JAK/STAT, NF-kB, and PI3-kinase/AKT, which help regulate cancer cell growth and inflammation.
  • Future research is necessary to establish effective dosages for humans and to create new forms of GS that enhance its therapeutic effects, paving the way for its application in cancer treatment.
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The deterioration of stored wheat due to pest infestations is a significant concern, with pests like , , , , , and being major contributors. This study examined the efficacy of spinosad and alpha-cypermethrin, individually and in combination, against these pests under laboratory conditions. Spinosad was tested at two concentrations (0.

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Pulses are considered a remarkable and stable source of nutrients, which are being presently extensively cultivated and consumed in different parts of the world. Pulses belong to the family Leguminosae and are a rich source of nutrients such as phosphorus (P) and nitrogen (N) for best growth via symbiotic relationship with bacteria and AMF (arbuscular mycorrhizal fungi). The aim of the current study was evaluating the influence of AMF diversity associated with various pulses (French bean, mung bean, kidney bean, peas, soybean, peanuts, and grams).

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, , , , , and are all major pests of stored grains. In this study, the efficiency of single and joint applications of the entomopathogenic nematode (EPN) at two different doses (50 and 100 IJs cm) and the entomopathogenic fungus (EPF) for the management of the aforementioned pests was estimated. At single treatments, both doses of caused higher mortality rates to all six pest species compared to .

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Background: Despite advancement in imaging techniques, the diagnosis of solid pancreatic lesions (SPLs) remains challenging. The latest advancement in elastography permits the quantitative measurements of the average elasticity of a lesion. Therefore, our main aim of this study was to determine the utility of endoscopic ultrasound-guided elastography (EUS-EG) and strain ratio (EUS-SR) in predicting SPLs.

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Cancer is still the leading cause of death worldwide, burdening the global medical system. Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a bioactive compound identified in plants such as Boraginaceae and Nepetoideae subfamilies of the Lamiaceae family, including Thymus masticmasti chinaythia koreana, Ocimum sanctum, and Hyptis pectinate. This updated review is to highlight the chemopreventive and chemotherapeutic effects of RA and its derivatives, thus providing valuable clues for the potential development of some complementary drugs in the treatment of cancers.

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(EA) mediated green chemistry route was used for the biofabrication of NiONPs without the provision of additional surfactants and capping agents. The formation of NiONPs was confirmed using advanced different characterization techniques such as Scanning electron microscopy, UV, Fourier transmission-infrared, RAMAN, and energy dispersal spectroscopic and dynamic light scattering techniques. Further, different biological activities of EA-NiONPs were studied.

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The current study evaluates the efficacy of the entomopathogenic fungus Beauveria bassiana (Balsamo-Crivelli) Vuillemin (Hypocreales: Cordycipitaceae), diatomaceous earth (DE) (Protect-It), and the oxadiazine indoxacarb, at single or combined applications on wheat kernels, for the management of the rusty grain beetle, Cryptolestes ferrugineus (Stephens) (Coleoptera: Laemophloeidae), the red flour beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae), the khapra beetle, Trogoderma granarium Everts (Coleoptera: Dermestidae), and the lesser grain borer, Rhyzopertha dominica (F.) (Coleoptera: Bostrychidae). The study was conducted between November 2020 and August 2021 in Faisalabad under a complete randomized block design.

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The current study examines the efficacy of the semi-synthetic insecticide spinetoram and entomopathogenic fungi Beauveria bassiana (Balsamo-Crivelli) Vuillemin (Hypocreales: Cordycipitaceae) as wheat protectants against the lesser grain borer, Rhyzopertha dominica (F.) (Coleoptera: Bostrychidae), the red flour beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae), the granary weevil, Sitophilus granarius (L.) (Coleoptera: Curculionidae), and the khapra beetle, Trogoderma granarium Everts (Coleoptera: Dermestidae), under laboratory and field trials.

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Introduction: Gallbladder cancer (GBC) is the most common malignant biliary tract tumor with the shortest survival from the time of diagnosis. This poor prognosis is due to the destructive biologic behavior of GBC, lack of sensitive screening tests for early detection, and vague nature of first presentation. Here in this study, we will evaluate the baseline characteristics of the patients presenting with gallbladder carcinoma in our population.

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This study presents an overview of the current situation of highly hazardous pesticides (HHPs) in North Africa and Near East countries (NENA). This work reviews the registered pesticides in the region and identify HHPs being used according to the criteria 1-8 for HHPs of FAO/WHO Guidelines on HHPs. In addition, to identify the weakness and the need of the region to mitigate the risk from the use of HHPs, the report ended with recommendations needed in the region to improve the pesticide managements and registration, such as improving the agricultural practices by adopting the integrated pest management IPM and including replacing HHPs with ecosystem-friendly alternatives if available.

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In the recent years, green synthesis of zinc oxide nanoparticles (ZnONPs) using plant extracts and phytochemicals has gained significant attention. In present research study, facile, green, and tunable ZnONPs were biosynthesized from Rhamnella gilgitica leaf aqueous extract as a strong reducing and stabilizing agents. The prepared ZnONPs@Rhamnella were characterized and validated using common nanotechnology techniques (UV-Vis, XRD, EDX, FT-IR, SEM, TEM, DLS, and Raman) and revealed spherical morphology with particle size ~21 nm.

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Article Synopsis
  • The study investigates the protective effects of methanol extracts from plants (PJM and PHM) on rat kidneys after exposure to a nephrotoxin called CCl, which induces oxidative stress and DNA damage.
  • Results showed that CCl caused significant declines in antioxidant enzyme levels and increased harmful biochemical markers in the rats, while co-administration of PJM and PHM helped restore these levels and improve kidney health.
  • The findings suggest that PJM and PHM may have therapeutic potential for treating oxidative stress-related kidney disorders and could be beneficial in cases of kidney trauma.
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Background: Grain size is an essential factor of grain quality and yield in rice. The genetic studies have substantially contributed to enhancing yield and maintaining a good quality of rice. The two major genes GS3 (a negative regulator of grain length) and GW2 (a negative regulator of grain width) with functional mutation play a significant role in controlling the grain size of rice.

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The GRAS (derived from GAI, RGA and SCR) gene family consists of plant-specific genes, works as a transcriptional regulator and plays a key part in the regulation of plant growth and development. The past decade has witnessed significant progress in understanding and advances on GRAS transcription factors in various plants. A notable concern is to what extent the mechanisms found in plants, particularly crops, are shared by other species, and what other characteristics are dependent on GRAS transcription factor (TFS)-mediated gene expression.

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Article Synopsis
  • The study focuses on the production of zinc oxide nanoparticles (ZnONPs) using leaf extracts from Elaeagnus angustifolia (EA), which provides a non-toxic method for synthesis.
  • Various analytical techniques confirmed the physical and chemical properties of the ZnONPs, revealing their nanoscale size and potential for various applications.
  • The ZnONPs demonstrated promising anticancer and antimicrobial activities, as well as strong antioxidant properties, indicating their potential for clinical development.
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The current study aims to investigate the anticancer potential of Periploca hydaspidis extracts against HCCLM3 and MDA-MB 231 cell lines with invasive properties and to identify molecular targets underlying its action mechanism. Cytotoxic screening of plant extracts was done via MTT assay against liver and breast cancer cell lines and GC/MS of the best cytotoxic fraction was performed to identify its chemical composition. Flow cytometry detected apoptosis and cell-cycle changes after drug treatment.

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  • - PJM, a methanol fraction, effectively inhibits cancer cell growth by targeting the STAT3 signaling pathway, reducing the activation of upstream kinases like JAK-1/2 and c-Src while enhancing STAT3 inhibitors and key pro-apoptotic proteins.
  • - The study demonstrated that PJM reduces oncogenic protein levels, leading to decreased cell proliferation, migration, and invasion, while triggering apoptosis through the activation of caspases and down-regulation of anti-apoptotic proteins.
  • - The findings suggest that PJM's anticancer effects are closely linked to the inhibition of STAT3, with further research needed to explore its potential role in preventing cancer metastasis.
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Plant heat stress response is a multi-factorial trait that is precisely regulated by the complex web of transcription factors from various families that modulate heat stress responsive gene expression. Global warming due to climate change affects plant growth and development throughout its life cycle. Adds to this, the frequent occurrence of heat waves is drastically reducing the global crop yield.

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