Deciphering glioblastoma: Unveiling imaging markers for predicting MGMT promoter methylation status.

Glioblastoma, the most common primary malignant tumor of the central nervous system in adults, is also among the most lethal. Despite a comprehensive treatment approach which utilizes surgery and postoperative chemoradiation, prognosis typically remains dismal. However certain epigenetic modifications, such as methylation of the MGMT promoter, have been proven to correlate with improved post-treatment outcomes.

A multi-institutional meningioma MRI dataset for automated multi-sequence image segmentation.

Meningiomas are the most common primary intracranial tumors and can be associated with significant morbidity and mortality. Radiologists, neurosurgeons, neuro-oncologists, and radiation oncologists rely on brain MRI for diagnosis, treatment planning, and longitudinal treatment monitoring. However, automated, objective, and quantitative tools for non-invasive assessment of meningiomas on multi-sequence MR images are not available.

The Brain Tumor Segmentation - Metastases (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI.

The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and benchmarking algorithms using rigorously annotated internationally compiled real-world datasets. This study presents the results of the segmentation challenge and characterizes the challenging cases that impacted the performance of the winning algorithms.

Diffuse Idiopathic calcinosis cutis: a case report in a 13-year-old Syrian boy.

Calcinosis cutis is characterized by the deposition of calcium salts in the skin and subcutaneous tissue. It is divided into the following subtypes: dystrophic, metastatic, iatrogenic, idiopathic and calciphylaxis. In this case, we report a 13-year-old Syrian boy with idiopathic calcinosis cutis, the lesions were unusually widespread, unlike the common condition which is usually localized to one area.

The substantial awareness role of web-based and social media platforms in developing countries during a pandemic scenario: the example of COVID-19.

Background: During the outbreak of coronavirus COVID-19, social media platforms have shown effectiveness in information dissemination. Delivering evidence-based medical knowledge and trustworthy recommendations is a difficult mission for classical entities, especially in a war-torn country with a fragile health system. In this context, the role of non-governmental scientific organizations was proven, filling the gap between original scientific sources and a non-English speaking population.

Ollier disease: the first report in Syria.

Ollier disease is a rare nonhereditary skeletal disorder, characterized by multiple enchondromas, which are noncancerous growth of cartilage. In this report, we present a case of Ollier disease in a 10-year-old Syrian boy. The patient presented with multiple boney masses on hands; he had a history of pathological fractures when he was 5, which caused crippling.