Publications by authors named "Yasar T Esengul"
Objective: Stereotactic laser amygdalohippocampotomy (SLAH) is an appealing option for patients with temporal lobe epilepsy, who often require intracranial monitoring to confirm mesial temporal seizure onset. However, given limited spatial sampling, it is possible that stereotactic electroencephalography (stereo-EEG) may miss seizure onset elsewhere. We hypothesized that stereo-EEG seizure onset patterns (SOPs) may differentiate between primary onset and secondary spread and predict postoperative seizure control.
View Article and Find Full Text PDFSource localization of ictal SEEG to predict postoperative seizure outcome.
Clin Neurophysiol
December 2022
Objective: Stereo-electroencephalography (SEEG) is inherently-three-dimensional and can be modeled using source localization. This study aimed to assess the validity of ictal SEEG source localization.
Methods: The dominant frequency at ictal onset was used for source localization in the time and frequency domains using rotating dipoles and current density maps.
Article Synopsis
- The study aimed to find scalp EEG patterns related to hippocampal spikes in patients with mesial temporal lobe epilepsy (mTLE).
- Researchers recorded EEG signals from the scalp and brain simultaneously in 20 patients and analyzed the correlation during sleep.
- The results showed varied rates of hippocampal spikes, with some correlating with different types of scalp EEG discharges, suggesting that small sharp spikes (SSS) might serve as a significant indicator for diagnosing mTLE.
Article Synopsis
- SEEG allows for better visualization of brain activity related to epilepsy beyond just the electrodes themselves, potentially improving analysis and interpretation.
- The study aimed to validate a method for localizing the source of epileptic activity and evaluate its effectiveness in monitoring regions in the brain that aren't directly implanted with electrodes.
- Results indicated that this new method showed high sensitivity and specificity in predicting certain outcomes related to surgical intervention but struggled to correlate with actual seizure outcomes, suggesting further refinement is needed.