Photodynamic Therapy for Glioblastoma: Illuminating the Path toward Clinical Applicability.

Glioblastoma (GBM) is the most common adult brain cancer. Despite extensive treatment protocols comprised of maximal surgical resection and adjuvant chemo-radiation, all glioblastomas recur and are eventually fatal. Emerging as a novel investigation for GBM treatment, photodynamic therapy (PDT) is a light-based modality that offers spatially and temporally specific delivery of anti-cancer therapy with limited systemic toxicity, making it an attractive option to target GBM cells remaining beyond the margins of surgical resection.

Violation of Heisenberg's measurement-disturbance relationship by weak measurements.

While there is a rigorously proven relationship about uncertainties intrinsic to any quantum system, often referred to as "Heisenberg's uncertainty principle," Heisenberg originally formulated his ideas in terms of a relationship between the precision of a measurement and the disturbance it must create. Although this latter relationship is not rigorously proven, it is commonly believed (and taught) as an aspect of the broader uncertainty principle. Here, we experimentally observe a violation of Heisenberg's "measurement-disturbance relationship", using weak measurements to characterize a quantum system before and after it interacts with a measurement apparatus.

Closed timelike curves via postselection: theory and experimental test of consistency.

Closed timelike curves (CTCs) are trajectories in spacetime that effectively travel backwards in time: a test particle following a CTC can interact with its former self in the past. A widely accepted quantum theory of CTCs was proposed by Deutsch. Here we analyze an alternative quantum formulation of CTCs based on teleportation and postselection, and show that it is inequivalent to Deutsch's.