Publications by authors named "Yaryna Dyakiv"
Background: Mitral valve (MV) disease including myxomatous degeneration is the most common form of valvular heart disease with an age-dependent frequency. Genetic evidence indicates that mutations of the human transcription factor are associated with MV defects, including MV regurgitation. In this study, we sought to determine whether murine and its closely related factor, , are required in valvular endothelial cells (VECs) for the maintenance of MV leaflets, including VEC junctions and the stratified trilaminar ECM (extracellular matrix).
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- - Cross-linked β-cyclodextrin (β-CD) polymers serve as effective adsorbents for removing harmful per- and polyfluoroalkyl substances (PFAS) from water sources, showcasing their potential in treating contaminated environments.
- - The study evaluates 20 different StyDex polymer variations with different comonomer structures and configurations, identifying one with dimethylbutyl ammonium ions as the best performer for PFAS adsorption in batch tests.
- - The research highlights that the arrangement of styrene groups on β-CD monomers did not significantly affect performance, suggesting a simpler preparation method that maintains effectiveness, paving the way for cost-efficient adsorbent development.
Background: Mitral valve (MV) disease including myxomatous degeneration is the most common form of valvular heart disease with an age-dependent frequency. Genetic evidence indicates mutations of the transcription factor are associated with MV defects, including mitral valve regurgitation. In this study, we sought to determine whether murine and its closely related factor, , are required in valvular endothelial cells (VECs) for the maintenance of MV leaflets, including VEC junctions and the stratified trilaminar extracellular matrix (ECM).
View Article and Find Full Text PDFIntestinal ischemia underlies several clinical conditions and can result in the loss of the intestinal mucosal barrier. Ischemia-induced damage to the intestinal epithelium is repaired by stimulation of intestinal stem cells (ISCs), and paracrine signaling from the vascular niche regulates intestinal regeneration. Here, we identify FOXC1 and FOXC2 as essential regulators of paracrine signaling in intestinal regeneration after ischemia-reperfusion (I/R) injury.
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