A femtosecond pulse downconverts broadband electromagnetic signals to the hundreds of MHz range, enabling fast measurement and enhancing electromagnetic monitoring efficiency. However, due to the high peak power of optical pulses, the received power of the detector is severely limited, and thus the sensitivity of the system is reduced. To address this problematic issue, this paper presents a multichannel parallel high-saturation optical power-balanced photodetection technique that uses parallel reception to enhance the detector's received power, thereby improving the signal-to-noise ratio (SNR) and system sensitivity.
View Article and Find Full Text PDFCilia are highly specialized cellular projections emanating from the cell surface, whose defects contribute to a spectrum of diseases collectively known as ciliopathies. Intraflagellar transport protein 88 (IFT88) is a crucial component of the intraflagellar transport-B (IFT-B) subcomplex, a protein complex integral to ciliary transport. The absence of IFT88 disrupts the formation of ciliary structures; thus, animal models with IFT88 mutations, including the oak ridge polycystic kidney (ORPK) mouse model and IFT88 conditional allelic mouse model, are frequently employed in molecular and clinical studies of ciliary functions and ciliopathies.
View Article and Find Full Text PDFObjectives: To evaluate the frequency of erectile dysfunction in male patients who undergo thyroidectomy using the International Index of Erectile Function (IIEF-5), and explore possible risk factors.
Methods: 163 male patients who undergo partial, unilateral or bilateral thyroidectomy between December 2021 and September 2022 were retrospectively studied. The IIEF-5 questionnaires were completed 6 and 12 months after surgery, and patients who reported erectile dysfunction (ED) before surgery were not included.
Pine wood nematodes (PWN, Bursaphelenchus xylophilus) cause widespread mortality in pine forests via pine wilt disease (PWD). The rapid death of diseased trees, which destroys biodiversity and significantly affects forest carbon storage, leading to negative environmental and economic consequences, as forests are crucial to the global carbon cycle. The interactions among PWN, hosts, and vector insects are closely linked to climate change.
View Article and Find Full Text PDFEthnopharmacological Relevance: Chinese herbal medicine constitutes a substantial cultural and scientific resource for the Chinese nation, attracting considerable scholarly interest due to its intrinsic characteristics of "multi-component, multi-target, and multi-pathway" interactions. Simultaneously, it aligns accurately with the intricate and continuously evolving progression of non-small cell lung cancer (NSCLC). Furthermore, contemporary pharmacological studies indicate that natural herbaceous plants and their bioactive compounds exhibit a diverse array of biological activities, including antioxidant, anti-inflammatory, and anti-tumor effects, among others.
View Article and Find Full Text PDFAmbient hypoxia can pose a major threat to the survival of metazoan organisms, especially insect embryos. Hemocyanin exhibits dominant expression in insect embryos, but its specific roles in hypoxia adaptation remain unexplored. Soil-dwelling locust eggs may frequently experience hypoxia during development.
View Article and Find Full Text PDFBackground: Although several models have been developed to predict postoperative pneumonia in elderly hip fracture patients, no systematic review of the model quality and clinical applicability has been reported.
Objective: To systematically review and critically appraise existing models for postoperative pneumonia in elderly hip fracture patients.
Design: Systematic review and meta-analysis.
Background: SM-like (LSM) genes a family of RNA-binding proteins, are involved in mRNA regulation and can function as oncogenes by altering mRNA stability. However, their roles in B-cell progression and tumorigenesis remain poorly understood.
Methods: We analyzed gene expression profiles and overall survival data of 123 patients with mantle cell lymphoma (MCL).
Biomed Phys Eng Express
September 2024
Int Immunopharmacol
December 2024
Biomass fly ash is a sustainable, eco-friendly cement substitute with economic and performance benefits, being renewable compared to coal fly ash. This study examines using biomass fly ash (BFA) as a sustainable cement substitute, comparing it with Class F fly ash (CFA). With a water-binder ratio of 0.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
July 2024
In the backdrop of the rapid evolution of the digital economy, the intricate relationship between digital industry agglomeration (DIA) and manufacturing firms' carbon emissions has become crucial for countries to achieve sustainable development. This study delves into this complex dynamic by analyzing data from Chinese-listed manufacturing companies spanning the years 2014 to 2021. A regional-level DIA Index is calculated to explore its impact on manufacturing firms' carbon emissions.
View Article and Find Full Text PDFDeveloping efficient and eco-friendly technologies for treating the antibiotic wastewaters is crucial. At present, the catalysts with metal-nitrogen (M-N) coordination showed excellent Fenton-like performance but were always difficult to realize practical antibiotics degradation because of their complicated preparation methods and inferior stability. In this work, the Co-N configuration was facilely reconstructed on the surface of CoO (Co-N/CoO), which exhibited superior catalytic activity and stability towards various antibiotics.
View Article and Find Full Text PDFCurrently, there are still many patients who require outpatient triage assistance. ChatGPT, a natural language processing tool powered by artificial intelligence technology, is increasingly utilized in medicine. To facilitate and expedite patients' navigation to the appropriate department, we conducted an outpatient triage evaluation of ChatGPT.
View Article and Find Full Text PDFPeriodontitis, which is related to various systemic diseases, is a chronic inflammatory disease caused by periodontal dysbiosis of the microbiota. Multiple factors can influence the interaction of periodontitis and associated inflammatory disorders, among which host immunity is an important contributor to this interaction. Innate immunity can be activated aberrantly because of the systemic inflammation induced by periodontitis.
View Article and Find Full Text PDFDesert ecosystems are sensitive to nitrogen (N) deposition. Considering snow is an important source of soil water, which is vital for plant growth and the biogeochemical cycle in desert areas. The effects of N deposition on biological soil crusts (BSCs) could be impacted by the removal of snow-cover.
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