Publications by authors named "Yaru Duan"
Article Synopsis
- - The study investigates the genetic basis of the peel stripe margin pattern in watermelons by crossing two distinct lines with different margin appearances, revealing a single recessive gene responsible for the clear pattern.
- - Genetic mapping techniques identified a specific location on chromosome 6 that contains a MYB transcription factor gene, with two significant mutations linked to the clear stripe pattern.
- - Further analysis of gene expression and transcriptomic data during key developmental stages suggests that numerous transcription factors and metabolic processes contribute to the differences in peel patterns between the two watermelon lines.
The wine flavour profile directly determines the overall quality of wine and changes significantly during bottle aging. Understanding the mechanism of flavour evolution during wine bottle aging is important for controlling wine quality through cellar management. This literature review summarises the changes in volatile compounds and non-volatile compounds that occur during wine bottle aging, discusses chemical reaction mechanisms, and outlines the factors that may affect this evolution.
View Article and Find Full Text PDFPurpose: This study is aimed at evaluating serum autoantibodies against four tumor-associated antigens, including LRDD, STC1, FOXA1, and EDNRB, as biomarkers in the immunodiagnosis of ovarian cancer (OC).
Methods: The autoantibodies against LRDD, STC1, FOXA1, and EDNRB were measured using an enzyme-linked immunosorbent assay (ELISA) in 94 OC patients and 94 normal healthy controls (NHC) in the research group. In addition, the diagnostic values of different autoantibodies were validated in another independent validation group, which comprised 136 OC patients, 136 NHC, and 181 patients with benign ovarian diseases (BOD).
Article Synopsis
- Serum autoantibodies against PDLIM1 could serve as effective biomarkers for diagnosing ovarian cancer (OC), based on their higher prevalence in OC patients compared to those with benign conditions or healthy individuals.
- Immunohistochemistry results showed that 84.3% of ovarian cancer tissues expressed PDLIM1, while adjacent and normal tissues did not, indicating a strong association with OC.
- When combined with the existing biomarker CA125, the anti-PDLIM1 autoantibody significantly improved detection rates for ovarian cancer, identifying 79.2% of cases compared to lower rates when using CA125 or anti-PDLIM1 alone.
Article Synopsis
- Autoantibodies against tumor-associated antigens (TAAbs) can serve as potential biomarkers for detecting gastric cancer (GC).
- The study used human proteomic chips to identify 11 candidate TAAbs linked to GC and validated them through ELISA in separate cohorts.
- A diagnostic model highlighting four specific TAAbs (anti-NRAS, anti-MFGE8, anti-PTP4A1, and anti-RRAS2) demonstrated strong performance in distinguishing GC patients from healthy controls, indicating the effectiveness of this approach for cancer detection.