Publications by authors named "Yarrow S Linden"

Enteric viruses, such as poliovirus, are a leading cause of gastroenteritis, which causes 2-3 million deaths annually. Environmental surveillance of wastewater supplements clinical surveillance for monitoring enteric virus circulation. However, while many environmental surveillance methods require liquid samples, some at-risk locations utilize pit latrines with waste characterized by high solids content.

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Ultraviolet (UV) devices emitting UVC irradiation (200-280 nm) have proven to be effective for virus disinfection, especially on surfaces and in air, due to their rapid effectiveness and limited to no material corrosion. Numerous studies of UV-induced inactivation focused on nonenveloped viruses. Little is known about UVC action on enveloped viruses across UVC wavelengths.

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Article Synopsis
  • - Environmental surveillance of poliovirus (PV) is crucial for global eradication efforts, with the bag-mediated filtration system (BMFS) enhancing effectiveness compared to the WHO's two-phase grab method.
  • - The study improved the BMFS for use in wastewater and surface waters in Nairobi by modifying aspects such as bag size and filter design to increase efficiency.
  • - The enhanced BMFS can concentrate larger volumes of water (3-10 L down to 10 mL), resulting in a 6-20 times greater effective volume assayed than the WHO method, potentially reducing false-negative results and simplifying logistics for virus detection.
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