Publications by authors named "Yariv Maron"
Selectivity to orientations of edges is seen at the earliest stages of visual processing in retinal orientation-selective ganglion cells (OSGCs), which are thought to prefer vertical or horizontal orientation. However, because stationary edges are projected on the hemispherical retina as lines of longitude or latitude, how edge orientation is encoded and decoded by the brain is unknown. Here, by mapping the orientation selectivity (OS) of thousands of OSGCs at known retinal locations in mice, we identify three OSGC types whose preferences match two longitudinal fields and a fourth type matching two latitudinal fields, with the members of each field pair being non-orthogonal.
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- The study investigates well-differentiated low-grade lung neuroendocrine tumors (LNETs), focusing on their classification and unique molecular profiles beyond the typical and atypical categories.
- Researchers used genomic techniques to reveal three distinct regulatory subtypes of LNETs, each characterized by specific transcription factors and differentiation signals: "proneuronal," "luminal-like," and "HNF+."
- Targeting the FGFR signaling pathway in the HNF+ subtype showed promise for reducing tumor growth, highlighting potential new therapeutic approaches for treating these tumors.