Effect of Partial or Complete Replacement of Dietary Inorganic Trace Minerals Supplement with an Advanced Chelated Source on Nutrient Digestibility in Sheep.

The delicate balance of trace mineral supplementation is critical for optimizing rumen function and overall ruminant health. This study evaluated the solubility of an advanced chelate technology-based supplement and assessed its impact on rumen degradability and apparent total tract digestibility (ATTD) when replacing inorganic sources. The solubility of the advanced trace minerals supplement (ACTM) was assessed at pH 5 and pH 2.

Development a risk assessment method for dimensional stone quarries.

Over the last 20 years, the global production of dimension stones has grown rapidly. Today, seven countries-China, India, Turkey, Iran, Italy, Brazil, and Spain-account for around two-thirds of the world's output of dimension stones. Each one has annual production levels of nine to over twenty-two million tons.

A smart look at monitoring while drilling (MWD) and optimizing using acoustic emission technique (AET).

Monitoring while drilling (MWD) is a crucial task in mining operations. Accurately measuring drill and rock-related operating parameters can significantly reduce the cost of drilling operations. This study explores the potential of monitoring drilling specific energy (SE) and optimizing drilling operations by processing vibroacoustic signals generated while drilling.

Cereal type and conditioning temperature altered protein and carbohydrate molecular structure, nutrient retention and performance in broilers fed pellet diets during starter and grower period.

1. Effects of cereal type and conditioning temperature (CT) on protein and carbohydrate (CHO) molecular structures, nutrient retention, carcass and blood characteristics, caecal microbial population and growth criteria of broilers fed pellet diet were evaluated for a total period of 35 d.2.

Assessment of UV radiation effects on airborne mucormycetes and bacterial populations in a hospital environment.

Infections, such as mucormycosis, often result from inhaling sporangiospore present in the environment. Surprisingly, the extent of airborne Mucormycetes sporangiospore concentrations remains inadequately explored. This study aimed to assess the influence of UV radiation on microbial populations and Mucormycetes spore levels within a hospital environment in northern Iran.

Using Spirulina platensis as a natural biocoagulant for polystyrene removal from aqueous medium: performance, optimization, and modeling.

Microplastics (MPs) are newly recognized contaminants that result from the breakdown of plastics released into aquatic environments. This study focuses on the elimination of polystyrene (PS) using S. platensis, a natural biocoagulant, from aqueous solutions.

Broadband multi-wavelength Brillouin-Raman fiber laser with frequency switching.

We purpose and demonstrate the switchable multi-wavelength Brillouin-Raman fiber laser (MBRFL) through a bi-directional Raman pumping scheme. The laser structure is arranged in a linear cavity by including a physical mirror at one side of the cavity. The switching operation for MBRFL with single- and double-wavelength spacing is implemented by optimizing the Raman power distribution through a variable optical coupler.

The design of an energy plant and artificial intelligence-based optimization for pasteurization with the least amount of carbon emissions based on animal waste.

It has been known for a very long time that chemical energy may be converted into electrical energy by using biomass, considered a renewable energy source. In the study that is being presented here, an explanation and a presentation are offered on a one-of-a-kind hybrid system that generates dependable power and cooling by harnessing the chemical energy of biomass. An anaerobic digester takes in organic material and converts it into biomass by using the high-energy content of cow manure as fuel.

Plasma immobilization of azobenzene dye on polyamide 6 polymer.

Plasma treatment of polymeric materials is a cost-effective and efficient technique to modify the surface and change the constituent unit configuration. This research investigates the effects of argon DC glow discharge plasma on pure and DR1 dye-loaded polyamide 6 polymer films and stabilization of dye on the surface. Plasma breaks some bonds and activates the surface through creating reactive structures such as free radical sites on the surface and increases tertiary amides on the surface of polymer.

EVADR ceRNA transcript variants upregulate WNT and PI3K signaling pathways in SW480 and HCT116 cells by sponging miR-7 and miR-29b.

Long noncoding RNAs are cancer regulators and EVADR-lncRNA is highly upregulated in colorectal cancer (CRC). Accordingly, we aimed to functionally characterize the EVADR in CRC-originated cells. Firstly, during the amplification of EVADR full-length cDNA (named EVADR-v1), a novel/shorter variant (EVADR-v2) was discovered.

Glow discharge plasma stabilization of azo dye on PMMA polymer.

The effects of argon gas glow discharge plasma on the surface of DR1 dye-loaded PMMA polymer films are examined in this work. Plasma immobilizes the dye on the surface of polymer without using stabilizers. Argon plasma activates the surface through breaking some bonds and generation of radical sites.

Interplay between SARS-CoV-2-derived miRNAs, immune system, vitamin D pathway and respiratory system.

The new coronavirus pandemic started in China in 2019. The intensity of the disease can range from mild to severe, leading to death in many cases. Despite extensive research in this area, the exact molecular nature of virus is not fully recognized; however, according to pieces of evidence, one of the mechanisms of virus pathogenesis is through the function of viral miRNAs.

Altered expression of STAT genes in periodontitis.

Signal Transducer and Activator of Transcription (STAT) pathway is functionally located downstream of Janus kinases proteins and can integrate signals from diverse pathways, thus regulating several aspects of immune responses. Although contribution of STAT proteins in the pathogenesis of several inflammatory conditions has been confirmed, their role in the development of periodontitis has been less appraised. Thus, we assessed levels of STAT transcripts in the periodontal tissues and circulation of affected individuals compared with the corresponding controls.

Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial.

Background: The beneficial effects of polyphenols have been reported. This study aimed to investigate the effect of oral Ellagic acid (EA) supplement on insulin resistance (IR) and Fetuin-A and serum sirtuin1 (SIRT1) in type 2 diabetics.

Methods: In this double-blind, randomized clinical trial, 44 diabetic patients were selected.

Effect of extrusion of soybean meal on feed spectroscopic molecular structures and on performance, blood metabolites and nutrient digestibility of Holstein dairy calves.

Objective: Performance and physiological responses of dairy calves may change by using extruded soybean meal (ESBM) instead of common soybean meal (SBM) in starter feed. The aims of the current study were i) to determine the effect of extrusion processing of SBM on protein electrophoretic size, fourier transform infrared spectroscopy (FTIR) structures and Cornell Net Carbohydrate and Protein System (CNCPS) protein subfractions and ii) to determine the effect of substitution of SBM with ESBM in starter feed of Holstein heifer calves during pre and post-weaning on performance, nutrient digestibility, and blood metabolites.

Methods: The SBM was substituted with ESBM at the level of 0%, 25%, 50%, 75%, and 100% (dry matter [DM] basis).

Performance evaluation and design for variable threshold alarm systems through semi-Markov process.

In large industrial systems, alarm management is one of the most important issues to improve the safety and efficiency of systems in practice. Operators of such systems often have to deal with a numerous number of simultaneous alarms. Different kinds of thresholding or filtration are applied to decrease alarm nuisance and improve performance indices, such as Averaged Alarm Delay (ADD), Missed Alarm and False Alarm Rates (MAR and FAR).

Decreasing the immunogenicity of Erwinia chrysanthemi asparaginase via protein engineering: computational approach.

Immunogenicity of therapeutic proteins is one of the main challenges in disease treatment. L-Asparaginase is an important enzyme in cancer treatment which sometimes leads to undesirable side effects such as immunogenic or allergic responses. Here, to decrease Erwinase (Erwinia chrysanthemiL-Asparaginase) immunogenicity, which is the main drawback of the enzyme, firstly conformational B cell epitopes of Erwinase were predicted from three-dimensional structure by three different computational methods.

Influence of bone meal degelatinisation and calcium source and particle size on broiler performance, bone characteristics and digestive and plasma alkaline phosphatase activity.

1. The current experiment was performed to elucidate the effects of degelatinised bone meal (DBM) in combination with different particle sizes of limestone or oyster shell on broiler performance, bone characteristics and digestive and plasma alkaline phosphatase (ALP) activity. 2.

Association between Long Noncoding RNA ANRIL Expression Variants and Susceptibility to Coronary Artery Disease.

Animal cells possess thousands of long non-coding (lnc) RNAs, such as antisense noncoding RNA in the INK4 locus (), which have regulatory roles in the cells' molecular mechanisms, including X-chromosome inactivation, and developmental processes. These lnc RNAs are known to influence the extensive spectrum of age-related disorders. Accordingly, there is evidence for the role of these lnc RNAs in cardiovascular diseases, particularly coronary artery diseases (CAD).

Inoculation and co-inoculation of alfalfa seedlings with root growth promoting microorganisms (, and ) affect molecular structures, nutrient profiles and availability of hay for ruminants.

Inoculation of alfalfa seedlings with root growth promoting microorganisms under semi-arid climate condition may improve biomass production and nutritive value. The current study aimed to investigate the effect of inoculation of alfalfa seedlings with (Pi) and co-inoculating Pi with (Gi + Pi) or (Sm + Pi) on hay yield, chemical composition, molecular structures by Fourier transformed infrared (FTIR) spectroscopy, ruminal degradability and gas production. Seedlings were grown in experimental pots in a greenhouse until first cut and then transferred outside and cut a further 4 times.

Association of Increased Levels of lncRNA H19 in PBMCs with Risk of Coronary Artery Disease.

Objective: Considerable research shows that long non-coding RNAs, those longer than 200 nucleotides, are involved in several human diseases such as various cancers and cardiovascular diseases. Their significant role in regulating the function of endothelial cells, smooth muscle cells, macrophages, vascular inflammation, and metabolism indicates the possible effects of lncRNAs on the progression of atherosclerosis which is the most common underlying pathological process responsible for coronary artery disease (CAD). The aim of present study was to assess whether the expression of the lnc RNA H19 was associated with a susceptibility to CAD by evaluating the expression level of H19 in the peripheral blood.

Staphylokinase Enzyme: An Overview of Structure, Function and Engineered Forms.

Background: One of the most important causes of death in the modern lifestyle is acute ischemic stroke, which is related to thrombosis in the blood vessels. Staphylokinase (SAK), a fibrinolytic agent, which is produced mainly by Staphylococcus aureus, is an indirect activator of plasminogen and belongs to the third generation of fibrinolytic enzymes.

Methods: Considering the very low level of production and immunogenicity concerns of natural SAK produced by Staphylococcus aureus, attempts have been made to produce recombinant SAKs with high production levels, more fibrinolytic activities and low immunogenicity.

Feeding di-ammonium phosphate as a phosphorous source in finishing lambs reduced excretion of phosphorus in feces without detrimental effects on animal performance.

Objective: Phosphorous (P) sources with greater bioavailability might increase animal production efficiency and decrease environmental pollution. The objective of current study was to determine animal performance, nutrient digestibility, blood metabolites and fecal P concentration in finishing lambs fed a diet with either di-calcium phosphate (DCP) or di-ammonium phosphate (DAP) as a P source.

Methods: Twelve 4-month-old male lambs (initial body weight 24.