Patients with inflammatory bowel disease (IBD) treated with immunomodulators or biologics face a higher risk of infections and often experience malnutrition and vitamin deficiencies.*
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A clinical trial was conducted with 320 IBD patients to assess if a daily multivitamin and mineral supplement could lower infection rates compared to a placebo over a 24-week period.*
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The study's results showed no significant difference in infection rates between the two groups, indicating that the supplement did not reduce the risk of infections for patients in remission while on IBD treatments.*
An experimental therapy using Manuka honey via colon lavage was conducted on four patients with therapy-resistant infections following a three-day fidaxomicin treatment.
The procedure involved administering 300 mL of 15% Manuka honey via a spray catheter during an ileocolonoscopy, after which patients rested for two hours without defecating.
Results showed a decrease in microbial load and restoration of microbiota diversity, leading to complete cessation of watery stools and no symptoms, suggesting the potential for further clinical research.