Publications by authors named "Yaqiong Jie"
Background: Osteoclast differentiation plays a key role in orthodontic tooth movement (OTM). We aimed to explore the role of human periodontal ligament (hPDL) extracellular vesicles (EVs) in osteoclast differentiation and OTM.
Methods: The hPDL cells were exposed to 4.
Aim Of The Study: The present study is aimed to investigate the apoptosis-inducing effect of icaritin in human oral squamous cell carcinoma (OSCC) cells and the associated mechanisms.
Materials And Methods: KB and SCC9 cell lines were used as model cell lines. Effect of icaritin on apoptosis was analyzed by flow cytometry.
Article Synopsis
- Ectopic expression of the protein 14-3-3ζ is found in various cancers, including oral squamous cell carcinoma (OSCC), but its role in tumor-immune system interactions has not been previously studied.
- 14-3-3ζ knockdown in OSCC cells increased the expression of inflammatory cytokines, while introducing 14-3-3ζ decreased these cytokines in normal cells stimulated by inflammatory agents.
- The protein 14-3-3ζ interacts with Stat3, and disrupting this interaction alleviates the inhibitory effects of 14-3-3ζ on tumor inflammation, suggesting it may play a crucial role in modulating tumor inflammation and the immune response in OSCC.