Background: Serum albumin reflects nutritional status and is associated with postoperative complications and mortality. Delta albumin (ΔAlb), defined as the difference between preoperative and lowest postoperative levels, could predict complications and mortality, even with postoperative levels above 30 g/L prompting albumin infusions. This study aimed to assess how ΔAlb relates to outcomes in craniotomy patients with brain tumors.
View Article and Find Full Text PDFFront Immunol
December 2023
Purpose: This prospective study examined whether metabolism parameters obtained using the tracer F-AlFNOTA-fibroblast activation protein inhibitor (FAPI)-04 (denoted as F-FAPI-04) in positron emission tomography/computed tomography (PET/CT) can predict programmed death ligand-1 (PD-L1) expression in patients with locally advanced esophageal squamous cell carcinoma (LA-ESCC).
Patients And Methods: The 24 enrolled LA-ESCC patients underwent an F-FAPI-04 PET/CT scan. The maximum, mean, peak and standard deviation standard uptake values (SUVmax, SUVmean, SUVpeak and SUVsd), metabolic tumor volume (MTV), and total lesion FAP (TLF) expression of the primary tumor were collected.
Objective: To explore the value of F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/computed tomography(CT) in MYCN gene and chromosome 1p36 and 11 statuses in newly diagnosed pediatric NB(neuroblastoma) and GNB(ganglioneuroblastoma).
Methods: We retrospectively analyzed newly diagnosed patients with 48 NB and 12 with GNB in our hospital. The data obtained from the clinical medical records included age, sex, pathologic type, and laboratory parameters such as lactate dehydrogenase (LDH), neuron-specific enolase (NSE) and the status of MYCN gene and chromosome 1p36 and 11q.
True thymic hyperplasia (TTH) in children is rare and difficult to distinguish from other thymic tumors such as thymoma and thymic carcinoma. A 3-year-old girl underwent an F-fluorodeoxyglucose (F-FDG) positron emission tomography (PET)/computed tomography (CT) scan (F-FDG PET/CT) and a chest CT scan to evaluate an anterior mediastinal mass. F-FDG PET/CT revealed a mediastinal mass showing heterogeneously increased FDG uptake with a maximum standardized uptake value (SUVmax) of 7.
View Article and Find Full Text PDFInflammation is an important driver of atherosclerosis. Succinate is a new extracellular inflammatory alarm released by activated macrophages. Succinate is sensed by succinate receptor 1 (Sucnr1) and then transferred to effector cells.
View Article and Find Full Text PDFHeavily acceptor-doped CuSnS (CTS) shows promisingly large power factor () due to its rather high electrical conductivity () which causes a modest with a high electronic thermal conductivity ( ). In the present work, a strategy of carrier compensation through Sb-doping at the Sn site in CuSnCoS was investigated, aiming at tailoring electrical and phonon transport properties simultaneously. Rietveld analysis suggested a complex polymorphic microstructure in which the cation-(semi)ordered tetragonal phase becomes dominant over the coherently bonded cation-disordered cubic phase, as is preliminarily revealed using TEM observation, upon Sb-doping and Sb would substitute Sn preferentially in the tetragonal structure.
View Article and Find Full Text PDFFabrication of highly efficient all thermally activated delayed fluorescence (TADF) white organic light-emitting diodes (WOLEDs) through solution-process still remains a big challenge. Here, two encapsulated TADF molecules with a small singlet-triplet energy gap (Δ E) and high photoluminescence quantum yield (PLQY) were designed and synthesized as yellow emitters for solution-processed WOLEDs. The high current, power, and external quantum efficiencies of 41.
View Article and Find Full Text PDFThe CeO@ZSM-5 was prepared by the dipping method. We used ZSM-5 and CeO as the carrier and load components, respectively. The aim was to reduce the low concentration of Cr(VI) in simulated wastewater (the concentration of Cr(VI) ranged from 0.
View Article and Find Full Text PDFA manganese(iii,iv)-tungsten(vi) supercluster based on 72 manganese ions (48 MnIV and 24 MnIII) and 48 tungsten(vi) centers [{MnIV24MnIII12O28(H2O)23}2(W24O120)2]40- has been prepared from the carboxylic Mn12 cluster. Its structure comprises two unprecedented cage-like Mn36W24 cores linked via two Mn-O-W bonds, leading to a Mn72W48 assembly. The inorganic synthetic mechanism was investigated through different synthesis methods and comprehensive ESI-MS tests.
View Article and Find Full Text PDFAn innovative analytical method based on the off-line two-dimensional reversed-phase/reversed-phase liquid chromatography (2D-RPLC/RPLC) was established to separate the components of root of L. The chromatograms of ethyl acetate extract of root of L. on a phenyl/tetrazolium column (250 mm×4.
View Article and Find Full Text PDFThe development of simple, robust, and reliable microRNA (miRNA) detection methods is of great significance in the studies of the biological function of miRNAs, molecular diagnostics, treatment of diseases, and targeted drugs. In recent years, with the increasing development of miRNA research, lots of novel approaches were developed for the detection of miRNA in terms of sensitivity, specificity, multiplicity, in situ imaging, etc. In particular, nucleic acid amplification-based methods and many detection techniques such as droplet digital PCR (ddPCR), electrochemiluminescence (ECL), surface-enhanced Raman spectroscopy (SERS), and mass spectrometry (MS) have been employed widely for the highly sensitive detection of miRNA.
View Article and Find Full Text PDFEthylene responsive factor (ERF) subfamily transcription factors play an important role in plant abiotic and biotic stress tolerance. A cold responsive ERF, MfERF1, was isolated from Medicago falcata, an important forage legume that has great cold tolerance. Overexpression of MfERF1 resulted in an increased tolerance to freezing and chilling in transgenic tobacco plants, whereas down-regulation of the ortholog of MfERF1 in Medicago truncatula resulted in reduced freezing tolerance in RNAi plants.
View Article and Find Full Text PDFHow to maximize the number of desirable active sites on the surface of the catalyst and minimize the number of sites promoting undesirable side reactions is currently an important research topic. In this study, a new way based on the synergism to achieve the successful fabrication of an ordered heterobimetallic self-assembled monolayer (denoted as ) with a controlled composition and an excellent orientation of metals in the monolayer was developed. consisting of phenanthroline and Schiff-base groups was prepared, and its novel heterobimetallic (Cu and Pd) self-assembled monolayer anchored in silicon (denoted as ) with a controlled composition and a fixed position was fabricated and characterized by UV, cyclic voltammetry, Raman, X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), X-ray diffraction (XRD), inductively coupled plasma atomic emission spectroscopy (ICP-AES), and water-drop contact angle (WDCA) analyses.
View Article and Find Full Text PDFPostoperative chemoradiotherapy (CRT) with concurrent 5-fluorouracil is the standard care for gastric cancer patients after curative surgery. The previous studies revealed that the subgroup of patients with high recurrence risk would benefit most from adjuvant CRT. S-1, a novel oral fluorouracil, has showed very effective in metastatic gastric cancer and became the standard option for gastric cancer with D2 dissection.
View Article and Find Full Text PDFArundo donax L. reed based anion exchange resin (ALR-AE resin) was prepared by the amination reaction for the adsorption of nitrate from aqueous solution. The physicochemical properties of the ALR-AE resin as well as its adsorption properties for nitrate were measured.
View Article and Find Full Text PDFAbnormal fibrosis occurs during chronic hepatic inflammations and is the principal cause of death in hepatitis C virus and schistosome infections. Hepatic fibrosis (HF) may develop either slowly or rapidly in schistosome-infected subjects. This depends, in part, on a major genetic control exerted by genes of chromosome 6q23.
View Article and Find Full Text PDFJ Exp Clin Cancer Res
October 2009
Background: Apoptosis is a major mode of hematological tumor death after radiation. Early detection of apoptosis may be beneficial for cancer adaptive treatment. 99mTc-HYNIC-annexinV has been reported as a promising agent for in vivo apoptosis imaging.
View Article and Find Full Text PDFBoth the binding and releasing of ferric ions in C-, and N-terminal binding sites of human serum transferrin are different. To understand the difference here the interactions of aluminum with the ligands containing phenolic group(s), including 8-hydroxyquinoline, salicylic acid, N,N'-di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid, N,N'-ethylenebis[2-(o-hydroxyphenolic)glycine], and human serum apotransferrin, respectively, are investigated by using UV difference and fluorescence spectra methods in 0.1 M N-2-hydroxyethylpiperazine-N-2-ethanesulfonic acid at pH 7.
View Article and Find Full Text PDFThe influence of concentration on the helicoidal change of N-phthaloylchitosan (PhCh) solutions in Me2SO, DMAc and DMF was investigated by means of circular dichroism (CD). The critical concentrations to form liquid crystal phase in these three solvents were 43, 45 and 48 wt.%, respectively as measured with polarized optical microscope.
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