Nonlinear Optical and Ion Sensor Properties of Novel Molecules Conjugated by Click Chemistry.

The molecular structure, luminescence behavior, and electronic energy level of an organic optoelectronic materials are important parameters for its synthesis. The electro-optical properties can be changed by modifying the structure of the molecule to make the electronic energy level adjustable. In this article, a series of organic conjugated micro-molecules are successfully synthesized by linking small compound units.

Photoacoustic Effect of Near-Infrared Absorbing Organic Molecules via Click Chemistry.

Near-infrared dyes were developed to be contrast agents due to their ability to improve the productivity of photoacoustic (PA) imaging and photothermal therapy (PTT) treatments. During the article, we described in detail the PA and PT effects of a category of organic molecules. F-TCNQ could potentially cause a red-shift in the peak PA intensity.

HPLC determination of thiopurine nucleosides and nucleotides in vivo in lymphoblasts following mercaptopurine therapy.

Background: Mercaptopurine is a prodrug requiring intracellular activation to thiopurine nucleotides to exert antileukemic effect. We developed a reversed-phase liquid chromatographic assay for the quantification of mercaptopurine, thioguanine, and methylmercaptopurine nucleoside and nucleotide concentrations in the target tissue, the leukemic lymphoblast.

Methods: Leukemic blasts were isolated from peripheral blood and bone marrow by a standard Ficoll-hypaque procedure.