Correction to: Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia.

There was an isolated error relating to the Oh et al. study (1) within our recurrence-free survival analysis. When the reported estimates for Oh et al.

Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets.

We report an experimental approach to study the mechanosensitivity of cell-cell contact upon mechanical stimulation in suspended cell-doublets. The doublet is placed astride an hourglass aperture, and a hydrodynamic force is selectively exerted on only one of the cells. The geometry of the device concentrates the mechanical shear over the junction area.

Comparison of Flexural Properties of Bulk-fill Restorative/Flowable Composites and Their Conventional Counterparts.

The objectives of the study were to compare the flexural modulus and strength of restorative and flowable bulk-fill resin-based composites (RBCs) to their conventional counterparts and to determine the effects of conditioning environment on their flexural properties. The materials evaluated included three conventional RBCs (Filtek Z350, Tetric N Ceram, and Beautifil II), three restorative bulk-fill RBCs (Filtek Bulk-Fill Restorative, Tetric N Ceram Bulk-Fill, and Beautifil Bulk-fill Restorative), as well as three flowable bulk-fill RBCs (Filtek Bulk-Fill Flowable, Tetric N Flow Bulk-Fill, and Beautifil Bulk-Fill Flowable). Specimens were fabricated using customized stainless-steel molds, finished, measured, and randomly divided into four groups.

Condylar repair and regeneration in adolescents/young adults with early-stage degenerative temporomandibular joint disease: A randomised controlled study.

Background: Anterior repositioning splint (ARS) can facilitate regenerative condylar remodelling.

Objective: To determine the effect of ARS on osseous condylar changes in adolescents/young adults with early-stage degenerative joint disease (DJD).

Methods: Sixty-nine patients with early-stage temporomandibular joint (TMJ) DJD based on the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and cone beam computed tomography (CBCT) imaging were recruited and randomly allocated to two treatment groups: (a) conservative therapy with ARS and (b) conservative therapy without ARS.

Best Buy in Public Health or Luxury Expense?: The Cost-effectiveness of a Pediatric Operating Room in Uganda From the Societal Perspective.

Objective: To determine the cost-effectiveness of building and maintaining a dedicated pediatric operating room (OR) in Uganda from the societal perspective.

Background: Despite the heavy burden of pediatric surgical disease in low-income countries, definitive treatment is limited as surgical infrastructure is inadequate to meet the need, leading to preventable morbidity and mortality in children.

Methods: In this economic model, we used a decision tree template to compare the intervention of a dedicated pediatric OR in Uganda for a year versus the absence of a pediatric OR.

Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia.

Purpose: Cancer-related mortality, a leading cause of death worldwide, is often the result of metastatic disease recurrence. Anesthetic techniques have varying effects on innate and cellular immunity, activation of adrenergic-inflammatory pathways, and activation of cancer-promoting cellular signaling pathways; these effects may translate into an influence of anesthetic technique on long-term cancer outcomes. To further analyze the effects of propofol (intravenous) and volatile (inhalational gas) anesthesia on cancer recurrence and survival, we undertook a systematic review with meta-analysis.

Effects of non-surgical rapid maxillary expansion on nasal structures and breathing: A systematic review.

Objective: This systematic review aims to determine the effects of non-surgical rapid maxillary expansion (RME) on breathing and upper airway structures.

Materials And Methods: An electronic search of the scientific literature from January 2005 to June 2016 was done using Web of Science, Dentistry & Oral Sciences Source and PubMed databases. A combination of search terms "rapid maxillary expansion", "nasal", "airway" and "breathing" were used.

Injuries Associated With Standing Electric Scooter Use.

Importance: Since September 2017, standing electric scooters have proliferated rapidly as an inexpensive, easy mode of transportation. Although there are regulations for safe riding established by both electric scooter companies and local governments, public common use practices and the incidence and types of injuries associated with these standing electric scooters are unknown.

Objective: To characterize injuries associated with standing electric scooter use, the clinical outcomes of injured patients, and common use practices in the first US metropolitan area to experience adoption of this technology.

Associations between symptoms of temporomandibular disorders, quality of life and psychological states in Asian Military Personnel.

Background: Symptoms of Temporomandibular Disorders (TMD) could affect oral health-related quality of life (OHRQoL) and psychological distress.

Objective: This study aims to determine the prevalence of TMD symptoms, and impact of type and number of TMD symptoms on OHRQoL and psychological states among Asian military personnel.

Method: The study was conducted across 12 military dental centres using self-administered questionnaire comprising demographical data, DC/TMD symptom questionnaire, OHIP-14 and DASS-21.

From Procedure to Poverty: Out-of-Pocket and Catastrophic Expenditure for Pediatric Surgery in Uganda.

Background: Financial protection from catastrophic health care expenditure (CHE) and patient out-of-pocket (OOP) spending are key indicators for sustainable surgical delivery. We aimed to calculate these metrics for a hospital stay requiring surgery in Uganda's pediatric population.

Methods: A survey was administered to family members of postoperative patients in the pediatric surgical ward at Mulago Hospital.

A qualitative study of quality of life domains and subdomains relevant to patients with spondyloarthritis.

Aims: To identify quality of life (QoL) domains and subdomains relevant to patients with different spondyloarthritis (SpA) subtypes in Singapore, and to assess how identified QoL domains and subdomains map onto currently used patient-reported outcome measures (PROMs).

Methods: Nine focus group discussions (FGDs), including two previously conducted FGDs from the Updating the Psoriatic Arthritis Core Domain Set Study, were conducted with patients with SpA in Singapore. The FGDs were organized by SpA subtype and language spoken.

Prevalence of Sleep Bruxism and Its Association with Obstructive Sleep Apnea in Adult Patients: A Retrospective Polysomnographic Investigation.

Aims: To determine the prevalence of sleep bruxism (SB) in adult obstructive sleep apnea (OSA) patients, to assess the association between SB and OSA in terms of sleep macrostructure and respiratory parameters, and to determine possible OSA risk factors for SB.

Methods: Type I polysomnographic data of 147 adult OSA patients (mean age 44.6 ± 12.

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress.

Adherens junctions are tensile structures that couple epithelial cells together. Junctional tension can arise from cell-intrinsic application of contractility or from the cell-extrinsic forces of tissue movement. Here, we report a mechanosensitive signaling pathway that activates RhoA at adherens junctions to preserve epithelial integrity in response to acute tensile stress.

Dynamic and Static Flexural Appraisal of Resin-based Composites: Comparison of the ISO and Mini-flexural Tests.

The objective of this study was to determine the influence of specimen dimension and conditioning medium on the dynamic and static flexural properties of resin-based composites (RBCs). One conventional (Filtek Z350) and two bulk-fill RBCs (Filtek Bulk-fill and Beautifil-Bulk Restorative) were evaluated. Bar-shaped specimens with dimensions 25 × 2 × 2 mm (ISO flexural [IFT]) or 12 × 2 × 2 mm (mini-flexural [MFT]) were fabricated using customized stainless-steel molds, finished, measured, randomly divided into two groups, and conditioned in air or artificial saliva (SAGF) for seven days at 37°C.

Influence of Shrinkage and Viscosity of Flowable Composite Liners on Cervical Microleakage of Class II Restorations: A Micro-CT Analysis.

This study determined the influence of shrinkage and viscosity of flowable composite liners on the cervical microleakage of Class II restorations using micro-CT. Seven composites of varying viscosities were selected and included five giomers (Shofu Beautifil II [BF], Flow Plus F00 and F03 [F00 and F03], Flow F02 and F10 [F02 and F10]) and 2 nano-filled composites (3M-ESPE Filtek Z350 [Z350] and Filtek Z350 Flowable [Z350F]). Polymerization shrinkage (n=7) was assessed with the Acuvol volumetric shrinkage analyzer while complex viscosity was determined with the advanced rheometric expansion system at 25°C.

Association between temporomandibular disorders and pubertal development: A systematic review.

The aim of this systematic review (SR) was to determine the association between temporomandibular disorders (TMDs) and pubertal development. Due to the inadequacy of the conventional PICO (Population, Interventions, Comparisons and Outcome) format used for intervention-based SRs, the Joanna Briggs Institute's guidelines for synthesising evidence related to associations with a focus on aetiology were adopted. A search of the PubMed and LIVIVO databases covering the period from January 1980 to May 2018 yielded four publications, which fulfilled the inclusion criteria.

Bone-borne accelerated sutural expansion: A microcomputed tomography study in rabbits.

Introduction: In this study, we evaluated the effect of bone-borne accelerated expansion protocols on sutural separation and sutural bone modeling using a microcomputed tomography system. We also determined the optimum instant sutural expansion possible without disruption of bone modeling.

Methods: Sixteen New Zealand white rabbits, 20 to 24 weeks old, were randomly divided into 4 experimental groups.

Aortic valve replacement with annular enlargement via a right anterior minithoracotomy.

A minimally invasive approach to aortic valve replacement offers many advantages compared to the conventional median sternotomy. However, minimally invasive approaches are technically challenging. In this video tutorial, we describe an aortic valve replacement performed via a right anterior minithoracotomy, facilitated by the use of videoscopic and automated suturing technologies.

Temporomandibular disorder symptoms and their association with quality of life, emotional states and sleep quality in South-East Asian youths.

Population studies on the prevalence of temporomandibular disorders (TMD) and their associations with quality of life (QoL), emotional states and sleep quality in South-East Asian youths are not available. This cross-sectional study assessed the presence of TMD and their relationships to QoL, depression, anxiety, stress and sleep quality in a cohort of South-East Asian adolescents/young adults. Three hundred and sixty-two students from a polytechnic were enrolled in the study and completed an online questionnaire consisting of the Fonesca's Anamnestic Index (FAI), Oral Health Impact Profile for TMD (OHIP-TMD), Depression, Anxiety and Stress Scales-21 (DASS-21) and Pittsburgh Sleep Quality Index.

Editing of Chloroplast by PPR Editing Factor EMB2261 Is Essential for Development.

RNA editing in plastids is known to be required for embryogenesis, but no single editing event had been shown to be essential. We show that the mutation is lethal through a failure to express an editing factor that specifically recognizes the site. EMB2261 was predicted to bind the -element upstream of the site and genetic complementation with promoters of different strength followed by RNA-seq analysis was conducted to test the correlation between editing and expression.

Impact of dietary solvents on flexural properties of bulk-fill composites.

Objective: This study investigated the effect of dietary solvents on flexural strength and modulus of bulk-fill composites.

Materials And Methods: One conventional composite (Filtek Z350 [FZ]), two bulk-fill composites (Filtek Bulk-fill [FB] and Tetric N Ceram [TN]) and a bulk-fill giomer (Beautifil-Bulk Restorative [BB]) were evaluated. Specimens (12 × 2 × 2 mm) were fabricated using customized stainless steel molds.

Effect of beta-blockers on cancer recurrence and survival: a meta-analysis of epidemiological and perioperative studies.

Background: The biological perturbation associated with psychological and surgical stress is implicated in cancer recurrence. Preclinical evidence suggests that beta-blockers can be protective against cancer progression. We undertook a meta-analysis of epidemiological and perioperative clinical studies to investigate the association between beta-blocker use and cancer recurrence (CR), disease-free survival (DFS), and overall survival (OS).

Airway Relaxation Effects of Water-Soluble Sclerotial Extract From .

has a long history of use by the indigenous community within East Asia to treat a range of health conditions including asthma and chronic cough. To date, there is limited scientific evidence to support its therapeutic effects in relieving these airways conditions. In this study, we examined the effects of the different molecular weight fractions [high-molecular-weight (HMW), medium-molecular-weight (MMW), and low-molecular-weight (LMW)] obtained from the cold water sclerotial extract (CWE) of on airways patency using airway segments isolated from Sprague Dawley rat in an organ bath set-up.

A Cost-Effectiveness Analysis of a Pediatric Operating Room in Uganda.

Unlabelled: This study examines the cost-effectiveness of constructing a dedicated pediatric operating room (OR) in Uganda, a country where access to surgical care is limited to 4 pediatric surgeons serving a population of over 20 million children under 15 years of age.

Methods: A simulation model using a decision tree template was developed to project the cost and disability-adjusted life-years saved by a pediatric OR in a low-income setting. Parameters are informed by patient outcomes of the surgical procedures performed.