Publications by authors named "Yaozhong Wang"

Article Synopsis
  • Ganoderma lucidum (G. lucidum) is a traditional Chinese herb thought to help with mental relaxation and memory issues, possibly through its anti-neuroinflammatory effects via the gut-brain axis.
  • This study aimed to examine how polysaccharides from G. lucidum can help improve cognitive dysfunction, employing various extraction and analysis methods to characterize these compounds.
  • Results showed that the extracted polysaccharides (β-glucan) can reduce cognitive dysfunction by altering gut microbiota and inhibiting neuroinflammation through specific signaling pathways, while also boosting immune responses in the body.
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Objective: This study investigated the clinical effects and applicability of minimally invasive impacted teeth extraction using digital robots.

Methods: A marker was bonded to the non-surgical area before surgery. A Cone-Beam Computed Tomography (CBCT) scan was obtained and uploaded to the robot software to determine the drilling position of the ring drill.

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Curcumin, a polyphenol extracted from turmeric, is a potential alternative for the treatment of oral squamous cell carcinoma (OSCC) due to its remarkable anticancer activity and low systemic toxicity. To further enhance the anticancer activity and bioavailability of curcumin, we synthesized a curcumin analogue, AC17, by modifying the benzene ring and methylene group of curcumin. A soluble hyaluronic acid microneedle patch (AC17@HAMN) was developed to ensure accurate and safe delivery of AC17 to tumor tissues.

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Acid mine drainage (AMD) has global significance due to its low pH and elevated heavy metal content, which have received widespread attention. After AMD irrigation in mining areas, heavy metals are distributed among soil layers, but the influencing factors and mechanisms remain unclear. AMD contamination of surrounding soil is primarily attributed to surface runoff and irrigation and causes significant environmental degradation.

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Article Synopsis
  • Schwertmannite shows promise for effectively adsorbing oxyanions like AsO, CrO, and Sb(OH), with better performance achieved through controlled biomineralization techniques.
  • By adjusting the oxidation rate of Fe(II) and managing pH levels using alkali control, researchers improved the surface area and adsorption characteristics of schwertmannite.
  • The study found that this controlled synthesis enhances adsorption for As(V) and Sb(V) more than Cr(VI), with distinct mechanisms observed for each oxyanion based on the conditions used during the synthesis process.
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Acid mine drainage (AMD) contains high concentrations of heavy metals, causing serious environmental pollution. Current neutralization techniques fail to recover and utilize valuable heavy metals, and generate large quantities of hazardous sludge. Manganese (Mn) is generally present at high levels in AMD.

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Industrialized nations have witnessed a decline in environmental quality over the years. The potential of digitalization in mitigating environmental pollution is of significant interest. Drawing on firm-level data from listed Chinese companies between 2010 and 2020, including pollutant and financial metrics, this study investigates the influence of digitalization on industrial environmental pollution.

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Objective: To explore the clinical value of the Gleason score upgrading (GSU) prediction model after radical prostatectomy (RP) based on a Bayesian network.

Methods: The data of 356 patients who underwent prostate biopsy and RP in our hospital from January 2018 to May 2021 were retrospectively analysed. Fourteen risk factors, including age, body mass index (BMI), total prostate-specific antigen (tPSA), prostate volume, total prostate-specific antigen density (PSAD), the number and proportion of positive biopsy cores, PI-RADS score, clinical stage and postoperative pathological characteristics, were included in the analysis.

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The heavy-metal adsorbent ε-MnO was produced through a simple, one-step oxidation-reduction reaction at three different synthesis temperatures (25 °C, 50 °C and 75 °C) and their morphology and chemical-physical properties were compared. Of the three materials, MnO-25 had the largest specific surface area and the highest surface hydroxyl concentration. Its optimal performance was demonstrated by batch adsorption experiments with Pb, Cd and Cu.

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Introduction: During routine surgery, rapid hemostasis, especially the rapid hemostasis of internal organs, is very important. The emergence of in-situ electrospinning technology has fundamentally solved this problem. It exhibits a high speed of hemostasis, and no bleeding occurs after surgery.

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Purpose: This study aimed to assess the stability and survival rate of dental implants inserted with different site preparation techniques-piezoelectric inserts versus traditional rotary instruments.

Materials And Methods: Correlative research was located by searching articles in PubMed, EMBASE, and the Cochrane Library. This was accomplished independently by two different reviewers and supplemented by a manual search.

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Insufficient blood supply is associated with high levels of necrosis in reconstructive surgery. Restoring blood flow to undersupplied ischemic tissue is the most important impact factor determining skin flap viability. Dietary nitrate, a significant source of nitric oxide, has multiple physiological functions, including regulator of blood flow, angiogenesis, and vasodilatation.

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Purpose: To study the clinical effect of "gelatamp" colloidal silver gelatin sponge on preventing dry socket after extracting the mandibular impacted teeth.

Methods: 1350 teeth extracted from 976 patients who needed to extract the mandibular impacted teeth were divided into group A, group B and group C randomly. "Gelatamp" colloidal silver gelatin sponge was implanted into alveolar socket after teeth extraction in group A, with absorbable gelatin sponge was implanted into alveolar socket in group B and nothing was implanted into alveolar socket in group C.

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Objective: To investigate the frequency of mitochondrial DNA (mtDNA) D-loop hypervariable region II (HVR II) and hypervariable region III (HVR III) mutations in oral squamous cell carcinoma (OSCC) and their correlation to provide the new targets for the prevention and treatment of OSCC.

Methods: The D-loop HVR II and HVR III regions of mtDNA in seven cases with OSCC tissues, matched with paracancerous tissues and normal mucosa tissues from the same case, were amplified by polymerase chain raction (PCR), then were detected by direct sequencing to find the mutantsites after the comparison of all sequencing results with the mtDNA Cambridge sequence in the GenBank database.

Results: 82 (56 species) nucleotide changes, with 51(26 species) nucleotide polymorphism, were found after the comparison of all sequencing results with the mtDNA Cambridge sequence in the GenBank database.

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