Histamine deficiency deteriorates LPS-induced periodontal diseases in a murine model via NLRP3/Caspase-1 pathway.

Histamine is a versatile biogenic amine, generated by the unique enzyme histidine decarboxylase (Hdc). Accumulating evidence has proven that histamine plays important roles in numerous biological and pathophysiological processes. However, the role and mechanism of Hdc/Histamine signaling in periodontal diseases remain unclear.

Problem-based learning and case-based learning in dental education.

Background: Numerous novel teaching methods have been developed in recent times for use in medical education. Of these methods, problem-based learning (PBL) and case-based learning (CBL) have attracted the most attention. We evaluated and compared the efficiency of these two teaching methods in dental education and discussed the importance of teachers to these courses.

Do lncRNAs and circRNAs expression profiles influence discoid lupus erythematosus progression?-a comprehensive analysis.

Background: Long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs)are involved in the progression of discoid lupus erythematosus (DLE), but an understanding of their underlying mechanisms remains elusive. To explore the expression profiles of lncRNAs and circRNAs in DLE, we surveyed the lncRNA/circRNA and mRNA expression profiles in the epithelia of oral DLE and adjacent normal tissues.

Methods: The lesional and non-lesional lower lips of three DLE patients were analysed by RNA-sequencing (RNA-seq).

Functionalized epigallocatechin gallate copolymer inhibit dentin matrices degradation: Mechanical, solubilized telopeptide and proteomic assays.

Objectives: We investigated the biostability of dentin organic matrices treated with epigallocatechin gallate (EGCG) in comparison to chlorhexidine (CHX), both extracted from functionalized copolymers.

Methods: Copolymers were prepared with bis-GMA:TEGDMA and incorporated with 1% of EGCG or CHX (w/w). Blank copolymers were used as control.

Comparison of Adaptation between the Major Connectors Fabricated from Intraoral Digital Impressions and Extraoral Digital Impressions.

The objective was to compare the adaptation between the major connectors of removable partial dentures derived from intraoral digital impressions and extraoral digital impressions. Twenty-four volunteers were enrolled. Each volunteer received an intraoral digital impression and one extraoral digital impression digitized from conventional gypsum impression.

Accuracy of Intraoral Digital Impressions for Whole Upper Jaws, Including Full Dentitions and Palatal Soft Tissues.

Intraoral digital impressions have been stated to meet the clinical requirements for some teeth-supported restorations, though fewer evidences were proposed for larger scanning range. The aim of this study was to compare the accuracy (trueness and precision) of intraoral digital impressions for whole upper jaws, including the full dentitions and palatal soft tissues, as well as to determine the effect of different palatal vault height or arch width on accuracy of intraoral digital impressions. Thirty-two volunteers were divided into three groups according to the palatal vault height or arch width.

Anthocyanin incorporated dental copolymer: bacterial growth inhibition, mechanical properties, and compound release rates and stability by (1)h NMR.

Objective. To evaluate bacterial growth inhibition, mechanical properties, and compound release rate and stability of copolymers incorporated with anthocyanin (ACY; Vaccinium macrocarpon). Methods.

Fabrication of porous titanium implants by three-dimensional printing and sintering at different temperatures.

This study evaluated the feasibility of using three-dimensional printing (3DP) to fabricate porous titanium implants. Titanium powder was blended with a water-soluble binder material. Green, porous, titanium implants fabricated by 3DP were sintered under protective argon atmosphere at 1,200, 1,300, or 1,400°C.

[Studies on personalized porous titanium implant fabricated using three-dimensional printing forming technique].

Three-dimensional printing (3DP) forming technology can shape personalized porous implant material with complex shape and fine structure to meet the various needs of different patients. In this paper, the green parts of porous titanium implants with diameter 25 mm x 20 mm were prepared using 3DP, and then debinded at 500 degrees C under vacuum. Finally they were sintered in the argon gas at 1 300 degrees C.

Nasal prosthesis rehabilitation using CAD-CAM technology after total rhinectomy: a pilot study.

Purpose: This study describes a nose prosthetic rehabilitation using computer-aided design and manufacturing (CAD-CAM) technology after facial disfigurement because of a total rhinectomy.

Methods: A patient with a total rhinectomy was scheduled for a nasal prosthesis. Based on the 3-D model of the patient's face reconstructed with the CT data, a four-piece mould for the nasal prosthesis was prototyped using a CAD-CAM procedure.

[Digital diagnosis and treatment system for facial prostheses].

Conventional diagnosis and treatment for facial prostheses have setbacks and limitations, including complicated procedure, inefficiency, low accuracy and poor esthetics, which could not meet the demand for high quality of the prostheses of the patients. With the technology of the computer aided design and computer aided manufacture (CAD/CAM), the new era for diagnosis and treatment for facial prostheses has been started since the 1990's. The digital diagnosis and treatment system for facial prostheses has been formed during these ten years, which including the digital data acquisition of the facial defect, CAD for facial prostheses, rapid fabrication of the prostheses.

[A preliminary study on maxillofacial prosthesis using structured light three-dimensional scanning and rapid prototyping technique].

Objective: To evaluate application of three-dimensional reconstruction of the facial soft tissue by use of light three-dimensional scanning system and rapid prototyping and to lay a foundation for developing the computer aided design (CAD) and computer aided manufacture (CAM) system of the maxillofacial defect rehabilitation.

Methods: The left and right facial profiles of a volunteer were scanned with the light three-dimensional scanning system that was a self-developed one. The complete point and cloud data were obtained by transforming the image data with the Surfcaq software.

[A preliminary study on facial profile reconstruction using structured light three-dimensional scanning technique].

Objective: To evaluate the feasibility of facial profile reconstruction by use of structured light three-dimensional scanning technique.

Methods: Based on Gray-code and phase-shifting method, the self-developed three-dimensional optical measurement system was used to acquire the primitive point data of a volunteer's face and cast of the face. All the datum records were processed and analysed with Imageware and Geomagic software to reconstruct a three-dimensional face model.

[The role of the mouthguard in preventing sports-related oral-facial and dental traumas.].

Sports play a significant role in all nations worldwide. More and more people involve in sports so that the incidence of the oral-facial and dental traumas with accidents ascends. The treatment cost is considerable, and the sporters' lives will be influenced by these traumas.