Efficacy evaluation of a bivalent subunit vaccine against epidemic PEDV heterologous strains with low cross-protection.

Unlabelled: Variant (PEDV), which causes diarrhea and high mortality in piglets, has become a major pathogen, and co-epidemics of different subtypes of the virus have become a very thorny problem for the clinical prevention and control of PEDV. However, cross-protection between epidemic G2a and G2b subtype strains has not been observed, and there is currently no vaccine against both G2a and G2b strains. In this study, we demonstrate the low cross-protection between G2a and G2b strains with piglet immunization and challenge tests.

A health status estimation method based on interpretable neural network observer for HVs.

Estimating the health status is a crucial step in learning about the health of hypersonic vehicles beforehand. The estimation results can be used to detect abnormal states and provide data reference for fault diagnosis. However, certain conventional neural network-based estimate techniques rely heavily on data and have limited model interpretability, which challenges the accuracy of the estimation results.

Toxicity assessment and microbial response to soil antibiotic exposure: differences between individual and mixed antibiotics.

Increasing amounts of antibiotics are introduced into soils, raising great concerns on their ecotoxicological impacts on the soil environment. This work investigated the individual and joint toxicity of three antibiotics, tetracycline (TC), sulfonamide (SD) and erythromycin (EM) a whole-cell bioreporter assay. TC, SD and EM in aqueous solution demonstrated cytotoxicity, whilst soil exposure showed genotoxicity, indicating that soil particles possibly affected the bioavailability of antibiotics.

Negative correlations between cultivable and active-yet-uncultivable pyrene degraders explain the postponed bioaugmentation.

Bioaugmentation is an effective approach to remediate soils contaminated by polycyclic aromatic hydrocarbons (PAHs), but suffers from unsatisfactory performance in engineering practices, which is hypothetically explained by the complicated interactions between indigenous microbes and introduced degraders. This study isolated a cultivable pyrene degrader (Sphingomonas sp. YT1005) and an active pyrene degrading consortium (Gp16, Streptomyces, Pseudonocardia, Panacagrimonas, Methylotenera and Nitrospira) by magnetic-nanoparticle mediated isolation (MMI) from soils.

Recent advances in the application of magnetic FeO nanomaterials for the removal of emerging contaminants.

Emerging contaminants (ECs) are widely distributed and potentially hazardous to human health and the ecological system. However, traditional wastewater treatment techniques are not sufficient to remove ECs. Magnetic nanomaterials are made of ferromagnetic or superparamagnetic magnetic elements such as iron and nickel, which can be easily separated from the aqueous solution, making them ideal adsorbents for contaminants in water.

Electrically compensated, tattoo-like electrodes for epidermal electrophysiology at scale.

Epidermal electrophysiology is widely carried out for disease diagnosis, performance monitoring, human-machine interaction, etc. Compared with thick, stiff, and irritating gel electrodes, emerging tattoo-like epidermal electrodes offer much better wearability and versatility. However, state-of-the-art tattoo-like electrodes are limited in size (e.