Publications by authors named "Yaoxiang Yang"

Article Synopsis
  • - Excessive reactive oxygen species (ROS) hinder the healing of diabetic wounds, leading to chronic, non-healing conditions.
  • - Researchers developed a nanoparticle (MSN@Met-CeO) loaded with metformin and cerium oxide, which is integrated into a ROS-responsive hydrogel shaped as microneedles for optimal application.
  • - In tests on diabetic mice, the MSN@Met-CeO microneedles improved wound healing by reducing both intracellular and extracellular ROS, accelerating inflammation resolution, and boosting blood vessel formation, showcasing their potential for clinical use.
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Introduction: Immune checkpoint (IC) inhibitor-related immunotherapies have attracted considerable attention in hepatocellular carcinoma (HCC). High IC expression and high tumor infiltrating lymphocyte levels are the current indicators of sensitivity to IC inhibitors. Thus, it is imperative to apply precision medicine strategies for patient selection.

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Human umbilical cord mesenchymal stem cells (hUC-MSCs) have shown very attractive potential in clinical applications for the treatment of various diseases. However, the data about the reproductive and developmental toxicity of hUC-MSCs remains insufficient. Thus, we assessed the potential effects of intravenous injection of hUC-MSCs on reproduction and development in Sprague-Dawley rats.

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